As the average age of the world population increases, more people will face debilitating
aging-associated conditions, including dementia and stroke. Not only does the incidence of …

As the average age of the world population increases, more people will face debilitating
aging-associated conditions, including dementia and stroke. Not only does the incidence of …

Normal aging is characterized by declines in processing speed, learning, memory, and
executive function even in the absence of neurodegenerative diseases such as Alzheimer's …

Cerebral ischemia is a major cause of morbidity and mortality worldwide, being more
prevalent in the elderly. Ischemic stroke disrupts the blood-brain barrier, triggering multiple …

Microglial cells of the aged brain manifest signs of dysfunction that could contribute to the
worse neurological outcome of stroke in the elderly. Treatment with colony‐stimulating factor …

Background The immune cell compartment of the mammalian brain changes dramatically
and peripheral T cells infiltrate the brain parenchyma during normal aging. However, the …

Neurodegeneration in the aged population is the leading cause of death, disability, and
impaired quality of life worldwide. Among the many proposed mechanisms for …

CD11b expression is essential for immunity due to its role in cell motility and phagocytosis.
Leukocytes, including monocytes, neutrophils and macrophages, express CD11b. B …

细胞衰老和响应衰老的慢性炎症作为大脑老化的信号, 对衰老进程有着重要的影响,
也是诱发神经退行性变的主要危险因素. 回顾响应衰老和神经炎症的小胶质细胞对神经退行性 …

Ageing of the central nervous system results in a loss of both grey and white matter, leading
to cognitive decline. Additional injury to both the grey and white matter is documented in …