Krüppel-like factors (KLFs) belong to the zinc finger family of transcription factors, and their
function in the CNS is largely unexplored. KLF11 is a member of the KLF family, and we …

Background The long-term functional recovery of traumatic brain injury (TBI) is hampered by
pathological events, such as parenchymal neuroinflammation, neuronal death, and white …

Microvascular endothelial cell (EC) injury and the subsequent blood‐brain barrier (BBB)
breakdown are frequently seen in many neurological disorders, including stroke. We have …

Transcription factors play an important role in the pathophysiology of many neurological
disorders, including stroke. In the past three decades, an increasing number of transcription …

Peroxisome proliferator-activated receptor gamma (PPARγ) is emerging as a major
regulator in neurological diseases. However, the role of (PPARγ) and its co-regulators in …

Objective—Mutations in Krüppel like factor-11 (KLF11), a gene also known as maturity-onset
diabetes mellitus of the young type 7, contribute to the development of diabetes mellitus …

Krüppel-like factor 4 (KLF4) is a transcription factor with diverse and cell type-specific
functions and is associated with a variety of pathophysiological processes. Recently, it has …

Background Although inflammatory cell adhesion molecules (CAMs) and anti-inflammation
factor Kruppel-like transcription factor (KLF) 4 have all been reported to be induced after …

During an ischemic stroke normal brain endothelial function is perturbed, resulting in blood
brain barrier (BBB) breakdown with subsequent infiltration of activated inflammatory blood …

Background We have previously demonstrated that the expression of kruppel-like
transcription factor-4 (KLF-4) is upregulated in astrocytes following acute ischemic stroke …