Structural brain changes indicative of dementia occur up to 20 years before the onset of
clinical symptoms. Efforts to modify the disease process after the onset of cognitive …

Structural brain changes indicative of dementia occur up to 20 years before the onset of
clinical symptoms. Efforts to modify the disease process after the onset of cognitive …

Cerebrovascular pathologies (CVPs) are common pathologies associated with age-related
cognitive decline along with Alzheimer disease pathologies. The impact of CVP on the …

Imaging is critical in the diagnosis and treatment of dementia, particularly in vascular
cognitive impairment, due to the visualization of ischemic and hemorrhagic injury of gray …

Recent studies examining Alzheimer's disease (AD) and aging have noted a strong
association between cerebrovascular risk and cognitive decline and suggest that AD may in …

Subclinical cerebrovascular disease is frequently identified in neuroimaging studies and is
thought to play a role in the pathogenesis of cognitive disorders. Identifying the etiologies of …

Introduction Cerebrovascular disease (CVD) is not currently considered a core pathological
feature of Alzheimer's disease (AD), but mounting evidence suggests that concurrent CVD …

Vascular risk factors (eg hypertension, dyslipidemia and diabetes) are well known risk
factors for Alzheimer'disease. These vascular risk factors lead to vascular brain injuries …

Atrophy and cerebrovascular disease are the two most important magnetic resonance
imaging (MRI) characteristics in the evaluation of dementia. On MRI, atrophy is the primary …

Dementia is a contemporary global health issue with far reaching consequences, not only
for affected individuals and their families, but for national and global socio-economic …