Although the precise mechanisms contributing to secondary brain injury following traumatic
brain injury are complex and obscure, a number of studies have demonstrated that …

Although the precise mechanisms contributing to secondary brain injury following traumatic
brain injury are complex and obscure, a number of studies have demonstrated that …

There is a great clinical need to identify the underlying mechanisms, as well as related
biomarkers, and treatment targets, for traumatic brain injury (TBI). Neuroinflammation is a …

Millions of patients are suffering from ischemic stroke, it is urgent to figure out the
pathogenesis of cerebral ischemia–reperfusion (I/R) injury in order to find an effective cure …

Traumatic brain injury (TBI), an acquired brain injury imparted by a mechanical trauma to the
head, has significant ramifications in terms of long-term disability and cost of healthcare. TBI …

Treatment for traumatic brain injury (TBI) remains elusive despite compelling evidence from
animal models for a variety of therapeutic targets. The activation of the NLRP3 (Nucleotide …

Background Recently, several studies have demonstrated that the NLRP3 inflammasome
participates in detecting cellular damage and mediating inflammatory responses to aseptic …

Inflammatory response plays an important role in the pathogenesis of secondary damage
after traumatic brain injury (TBI). The inflammasome is a multiprotein complex involved in …

The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain
containing 3 (NLRP3) inflammasome-mediated inflammatory response has emerged as a …

NOD-like receptor (NLR) family pyrin domain-containing 1 (NLRP1) is a member of the NLR
family. The NLRP1 inflammasome consists of the NLRP1 protein, the adaptor protein …