Functional domains of the human B-myb gene product

H Nakagoshi, Y Takemoto, S Ishii - Journal of Biological Chemistry, 1993 - ASBMB
Three members of the human myb gene family (c-myb, A-myb, and B-myb) encode
transcriptional regulators that can bind to specific DNA sequences. High levels of c-myb …

[HTML][HTML] DNA binding activity and transcriptional activator function of the human B-myb protein compared with c-MYB.

G Mizuguchi, H Nakagoshi, T Nagase… - Journal of Biological …, 1990 - Elsevier
Three members of the myb gene family have been identified in human cDNA libraries c-myb,
A-myb, and B-myb. We compared the DNA binding properties of the B-myb and c-myb …

Transcription regulation by murine B-myb is distinct from that by c-myb

RJ Watson, C Robinson, EW Lam - Nucleic acids research, 1993 - academic.oup.com
The transcription regulatory properties of murine B-myb protein were compared to those of c-
myb. Whereas c-Myb trans-activated an SV40 early promoter containing multiple copies of …

The C-terminal domain of B-Myb acts as a positive regulator of transcription and modulates its biological functions

IH Oh, EP Reddy - Molecular and cellular biology, 1998 - Taylor & Francis
The myb gene family consists of three members, named A-, B-, and c-myb. All three
members of this family encode nuclear proteins that bind DNA in a sequence-specific …

An alternatively spliced isoform of B-Myb is a transcriptional inhibitor

S Horstmann, S Ferrari, KH Klempnauer - Oncogene, 2000 - nature.com
B-Myb is a highly conserved member of the Myb transcription factor family. The primary
transcript of the B-myb gene is spliced alternatively in two mRNAs which either contain or …

Characterization and cell cycle-regulated expression of mouse B-myb.

EW Lam, C Robinson, RJ Watson - Oncogene, 1992 - europepmc.org
We have isolated a full-length mouse B-myb cDNA clone and used this to examine cell cycle-
regulated expression of this gene. Mouse B-Myb was predicted to comprise 704 amino acids …

B-Myb, a repressed trans-activating protein

S Ansieau, E Kowenz-Leutz, R Dechend… - Journal of molecular …, 1997 - Springer
B-Myb belongs to a family of related transcription factors which share a unique DNA binding
domain. B-Myb plays an important role in regulation of the cell cycle. Its expression is …

The carboxyterminus of human c-myb protein stimulates activated transcription in trans

G Vorbrueggen, F Kalkbrenner… - Nucleic acids …, 1994 - academic.oup.com
The cellular c-myb gene encodes a transcription factor composed of a DNA-binding domain,
a transactivating domain and a regulatory domain located at its carboxy (C-) terminus. The …

The conserved DNA binding domain mediates similar regulatory interactions for A-Myb, B-Myb, and c-Myb transcription factors

JJ Rushton, SA Ness - Blood Cells, Molecules, and Diseases, 2001 - Elsevier
ABSTRACT The vertebrate A-Myb, B-Myb, and c-Myb proteins comprise a family of related
transcription factors that share a highly conserved DNA binding domain. Although all three …

The role of Myb proteins in normal and neoplastic cell proliferation

J Lyon, C Robinson, R Watson - Critical Reviews™ in …, 1994 - dl.begellhouse.com
The c-myb protooncogene is the prototype of a gene family that contains two other recently
described members, A-myb and B-myb. The c-myb gene encodes a transcription regulatory …