阿尔茨海默氏病的病理机制和治疗策略

Y Ju, KY Tam - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Alzheimer's disease is a rather complex neurodegenerative disease, which is attributed to a
combination of multiple factors. Among the many pathological pathways, synaptic …

Pathological mechanisms and therapeutic strategies for Alzheimer's disease

Y Ju, KY Tam - Neural regeneration research, 2022 - journals.lww.com
Alzheimer's disease is a rather complex neurodegenerative disease, which is attributed to a
combination of multiple factors. Among the many pathological pathways, synaptic …

Tau-targeted therapy in Alzheimer's disease: History and current state

A Jurcau, VS Nunkoo - Frontiers in Clinical Drug Research, 2021 - books.google.com
The two main histopathological hallmarks still required for the diagnosis of Alzheimer's
disease are the presence of amyloid plaques and intraneuronal neurofibrillary tangles …

[PDF][PDF] Tau-targeting therapy in Alzheimer's disease: Critical advances and future opportunities

Y Guo, S Li, LH Zeng, J Tan - Ageing Neurodegener. Dis, 2022 - f.oaes.cc
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by two
pathological hallmark lesions: extracellular plaques composed of β-amyloid (Aβ) peptide …

[PDF][PDF] Alzheimer's Disease Pathophysiology and Novel Treatment: An Update

A Mo - ijpmbs.com
Alzheimer's disease, a progressive and irreversible brain disorder predominantly affecting
the elderly, is influenced by age, smoking, and head trauma. It disrupts memory, cognition …

Alzheimer Disease 病因研究现状

肖飞, 曾昭淳 - 中风与神经疾病杂志, 2008 - zfysjjbzz.com
阿尔茨海默病(Alzheimer's disease, AD) 亦称老年性痴呆症. 是老年人中最常见的神经退行性
疾病之一. 其主要病理学特征是老年斑, 神经元纤维缠结和基底前脑胆碱能神经元蜕变[1] …

[PDF][PDF] Alzheimer's disease: from molecule to clinic

JZ Wang - Neuroscience Bulletin, 2014 - neurosci.cn
Alzheimer's disease (AD) is the most common neurodegenerative disorder and is
characterized pathologically by the progressive intracellular accumulation of neurofibrillary …

Current trends and updates in the treatment of Alzheimer's disease

NH Parikh, PK Parikh, HJ Rao, K Shah, BP Dave… - Alzheimer's Disease and …, 2024 - Elsevier
Alzheimer's disease (AD) is one the most prevalent multifactorial neurodegenerative
ailments of aging and is the leading cause of cognitive deficits with progressive impairment …

靶向tau 治疗阿尔茨海默病: 从机制到临床

J Ye, H Wan, S Chen, GP Liu - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
阿尔茨海默病影响老年人群最常见的神经退行性疾病, 其主要的病理特征包括细胞外淀粉样蛋白
β (Aβ) 斑块聚集和细胞内tau 蛋白形成的神经原纤维缠结积聚. 已出现基于淀粉样蛋白β …

Recent trends in treatment strategies for Alzheimer's disease and the challenges: A topical advancement

N Liu, X Liang, Y Chen, L Xie - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's Disease (AD) is an irreversible and progressive neurological disease that has
affected at least 50 million people around the globe. Considering the severity of the disease …