Blood–brain barrier permeability is associated with different neuroinflammatory profiles in Alzheimer's disease

M Bruno, CG Bonomi, F Ricci… - European journal of …, 2024 - Wiley Online Library
Introduction Inflammation is an important player in Alzheimer's disease (AD), whose effects
can be influenced by the blood–brain barrier (BBB). Here, we investigated the relationship …

Effect of Vascular Risk Factors on Blood-Brain Barrier and Cerebrospinal Fluid Biomarkers Along the Alzheimer's Disease Continuum: A Retrospective Observational …

F Ricci, A Martorana, CG Bonomi… - Journal of …, 2024 - content.iospress.com
Background: Blood-brain barrier (BBB) dysfunction could favor the pathogenesis and
progression of Alzheimer's disease (AD). Vascular risk factors (VRF) could worsen BBB …

Cerebrospinal fluid/plasma albumin ratio as a biomarker for blood-brain barrier impairment across neurodegenerative dementias

CS Musaeus, HS Gleerup, P Høgh… - Journal of …, 2020 - content.iospress.com
Background: Previous studies have shown an association between disruption of the blood-
brain-barrier (BBB) and dementias of different etiologies. The protein concentration of …

[HTML][HTML] Alzheimer's disease pathology: pathways between chronic vascular risk factors and blood-brain barrier dysfunction in a cohort of patients with different types …

J Gan, X Yang, G Zhang, X Li, S Liu… - Frontiers in Aging …, 2023 - frontiersin.org
Background Blood brain barrier (BBB) breakdown is considered a potential mechanism of
dementia. The Alzheimer's disease (AD) biomarkers and vascular factors are also …

Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-β protein transport across the blood-brain barrier in Alzheimer's …

Y Matsumoto, D Yanase… - Dementia and geriatric …, 2007 - karger.com
Abstract Background/Aims: Alterations in the blood-brain barrier (BBB) may play an
important role in the pathogenesis and treatment of Alzheimer's disease (AD). We …

Blood–brain barrier dysfunction as a cause and consequence of Alzheimer's disease

MA Erickson, WA Banks - Journal of Cerebral Blood Flow & …, 2013 - journals.sagepub.com
The blood–brain barrier (BBB) plays critical roles in the maintenance of central nervous
system (CNS) homeostasis. Dysfunction of the BBB occurs in a number of CNS diseases …

[HTML][HTML] Progression of blood-brain barrier leakage in patients with Alzheimer's disease as measured with the cerebrospinal fluid/plasma albumin ratio over time

CS Musaeus, HS Gleerup… - Journal of …, 2023 - content.iospress.com
Background: Studies have found a disruption of the blood-brain barrier (BBB) in patients
with Alzheimer's disease (AD), but there is little evidence of the changes in the BBB over …

[HTML][HTML] Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype

S Janelidze, J Hertze, K Nägga, K Nilsson… - Neurobiology of …, 2017 - Elsevier
Blood-brain barrier (BBB) dysfunction might be an important component of many
neurodegenerative disorders. In this study, we investigated its role in dementia using large …

Blood–brain barrier permeability in Alzheimer's disease: a case–control MRI study

JM Starr, AJ Farrall, P Armitage, B McGurn… - Psychiatry Research …, 2009 - Elsevier
Blood-brain barrier (BBB) dysfunction may contribute to the risk of Alzheimer's disease (AD).
Dynamic contrast-enhanced magnetic resonance imaging (MRI) was performed repeatedly …

Blood–brain barrier breakdown in relationship to Alzheimer and vascular disease

Z Lin, S Sur, P Liu, Y Li, D Jiang, X Hou… - Annals of …, 2021 - Wiley Online Library
Objective Blood–brain barrier (BBB) breakdown has been suggested to be an early
biomarker in human cognitive impairment. However, the relationship between BBB …