There are two main pathways of protein degradation in vivo: proteasome and lysosome. As
a conserved intracellular process, autophagy delivers cargoes such as proteins or …

Autophagy is a dynamic process of subcellular degradation, which has recently sparked
great interest as it is now recognized to be involved in various developmental processes and …

Introduction Small molecules targeting autophagy have been highly implicated as new
therapeutic agents to treat diseases of interest. With the increasing demand for autophagy …

Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …

Autophagy is a critical metabolic process that supports homeostasis at a basal level and is
dynamically regulated in response to various physiological and pathological processes …

Background Autophagy is an evolutionarily conserved turnover process for intracellular
substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) …

Autophagy is a degradation system for intracellular components. One of the roles of
autophagy is the prompt removal of damaged organelles. Another unique role is to supply …

In addition to tumors and aging that are associated with autophagy, many other diseases are
also regulated by autophagy, including liver disease, myopathy, immune pathogen infection …

Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …

The word autophagy is derived from the Greek roots “auto”(self) and “phagy”(eating) and
broadly refers to the cellular catabolic processes, in which cytoplasmic materials are …