背景1 型糖尿病(T1D) 是一种自身免疫性疾病, 其特征是胰腺β 细胞被浸润的免疫细胞所破坏.
有观点认为在T1D 的进展过程中胰岛β 细胞与免疫细胞具有双向的协同作用 …

Type 2 diabetes mellitus (T2DM) is a complex disease that is caused by an impairment in
the secretion of β-cell insulin and by a peripheral resistance to insulin. Most patients …

Type 1 Diabetes (T1D) occurs as a result of the autoimmune destruction of pancreatic β-cells
by self-reactive T cells. The etiology of this disease is complex and difficult to study due to a …

Genome-wide association studies (GWAS) have heralded a new era in susceptibility locus
discovery in complex diseases. For type 1 diabetes,> 40 susceptibility loci have been …

Significant progress has been made in elucidating genetic risk factors influencing Type 1
diabetes (T1D); however, features other than genetic variants that initiate and/or accelerate …

Type 1 diabetes (T1D) is a chronic metabolic disorder characterized by the autoimmune
destruction of insulin-producing pancreatic islet beta cells in genetically predisposed …

Understanding active proinflammatory mechanisms at and before type 1 diabetes mellitus
(T1DM) onset is hindered in humans, given that the relevant tissues are inaccessible and …

Background Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases
in the world with complicated pathogenesis. This study aimed to identify differentially …

Type 1 diabetes mellitus (T1DM) is a chronic disease resulting from destruction of insulin-
producing pancreatic β cells. Genetic and environmental factors contribute to T1DM onset …

Abstract Aims/Introduction The incidence of type 2 diabetes is increasing worldwide. Hepatic
insulin resistance and liver lipid accumulation contributes to type 2 diabetes development …