Production of Pyomelanin, a Second Type of Melanin, via the Tyrosine Degradation Pathway in Aspergillus fumigatus
J Schmaler-Ripcke, V Sugareva… - Applied and …, 2009 - Am Soc Microbiol
Aspergillus fumigatus is the most important airborne fungal pathogen of immunosuppressed
humans. A. fumigatus is able to produce dihydroxynaphthalene melanin, which is …
humans. A. fumigatus is able to produce dihydroxynaphthalene melanin, which is …
Melanin and pyomelanin in Aspergillus fumigatus: from its genetics to host interaction
U Perez-Cuesta, L Aparicio-Fernandez… - International …, 2020 - Springer
Aspergillus fumigatus is a worldwide-distributed saprophytic fungus and the major cause of
invasive aspergillosis. This fungus can produce two types of melanin …
invasive aspergillosis. This fungus can produce two types of melanin …
Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence
T Heinekamp, A Thywißen, J Macheleidt… - Frontiers in …, 2013 - frontiersin.org
The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two
types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin …
types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin …
Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response
In Aspergillus fumigatus, the conidial surface contains dihydroxynaphthalene (DHN)-
melanin. Six-clustered gene products have been identified that mediate sequential catalysis …
melanin. Six-clustered gene products have been identified that mediate sequential catalysis …
A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress
E Geib, M Gressler, I Viediernikova, F Hillmann… - Cell chemical …, 2016 - cell.com
Melanins are ubiquitous pigments found in all kingdoms of life. Most organisms use them for
protection from environmental stress, although some fungi employ melanins as virulence …
protection from environmental stress, although some fungi employ melanins as virulence …
Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus
V Sugareva, A Härtl, M Brock, K Hübner, M Rohde… - Archives of …, 2006 - Springer
Aspergillus fumigatus is an important pathogen of the immunocompromised host.
Previously, it was shown that the polyketide synthase encoded by the pksP (alb1) gene …
Previously, it was shown that the polyketide synthase encoded by the pksP (alb1) gene …
Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway
A Thywißen, T Heinekamp, HM Dahse… - Frontiers in …, 2011 - frontiersin.org
Aspergillus fumigatus is the most important air-borne fungal pathogen of humans. The
interaction of the pathogen with the host's immune system represents a key process to …
interaction of the pathogen with the host's immune system represents a key process to …
Laccases involved in 1, 8-dihydroxynaphthalene melanin biosynthesis in Aspergillus fumigatus are regulated by developmental factors and copper homeostasis
S Upadhyay, G Torres, X Lin - Eukaryotic cell, 2013 - Am Soc Microbiol
Aspergillus fumigatus produces heavily melanized infectious conidia. The conidial melanin
is associated with fungal virulence and resistance to various environmental stresses. This 1 …
is associated with fungal virulence and resistance to various environmental stresses. This 1 …
Mitogen-activated protein kinase cross-talk interaction modulates the production of melanins in Aspergillus fumigatus
AO Manfiolli, FS Siqueira, TF Dos Reis, P Van Dijck… - mbio, 2019 - Am Soc Microbiol
The pathogenic fungus Aspergillus fumigatus is able to adapt to extremely variable
environmental conditions. The A. fumigatus genome contains four genes coding for mitogen …
environmental conditions. The A. fumigatus genome contains four genes coding for mitogen …
Characterization of melanin pigment produced by Aspergillus nidulans
RCR Gonçalves, HCF Lisboa… - World Journal of …, 2012 - Springer
Although most of the Ascomycetes present DHN-melanin, some reports suggest that A.
nidulans does not produce this type of melanin. In this study, we analyzed the pigment …
nidulans does not produce this type of melanin. In this study, we analyzed the pigment …