Minimally invasive, direct, real time measurement of drug concentration in the anterior eye
Aims: To evaluate a corneal contact lens which effectively turns the anterior chamber of the
eye into a cuvette, enabling the concentration of a drug to be measured using absorption …
eye into a cuvette, enabling the concentration of a drug to be measured using absorption …
Measurement and quantification of fluorescent changes in ocular tissue using a novel confocal instrument
KK Buttenschoen, JM Girkin… - … : Photonic Solutions for …, 2014 - spiedigitallibrary.org
Our sight is a major contributor to our quality of life. The treatment of diseases like macular
degeneration and glaucoma, however, presents a challenge as the delivery of medication to …
degeneration and glaucoma, however, presents a challenge as the delivery of medication to …
Drug detection in the living eye using a novel, minimally invasive optoelectronic system
J Miller, WS Wilson, WK Kek, CG Wilson… - IEEE sensors …, 2003 - ieeexplore.ieee.org
We report the successful construction of an ocular spectrometer, with a hand-held sensor
head, connected to the rest of the instrument via two optical fibers. When this sensor head is …
head, connected to the rest of the instrument via two optical fibers. When this sensor head is …
角膜接触镜作为眼部药物递送系统的研究进展
俞振伟, 单纯蕾, 俞凌燕 - 中国药学杂志, 2018 - cqvip.com
角膜接触镜具有良好的生物相容性和较长的佩戴时间, 可以作为理想的眼部药物递送系统.
载药的角膜接触镜可以延长药物在眼部的停留时间, 提高生物利用度. 笔者综述了角膜接触镜 …
载药的角膜接触镜可以延长药物在眼部的停留时间, 提高生物利用度. 笔者综述了角膜接触镜 …
Design of a novel system for spectroscopy measurements of the aqueous humor
J Miller, DG Uttamchandani - Optical Fibers and Sensors for …, 2001 - spiedigitallibrary.org
The authors report on the design of a system which will enable real time measurements of
(therapeutic) drug concentrations in the anterior chamber of the eye. Currently the …
(therapeutic) drug concentrations in the anterior chamber of the eye. Currently the …
Validation of a device for transcorneal drug permeation measure
R Valls, ML García, MA Egea, O Valls - Journal of pharmaceutical and …, 2008 - Elsevier
A model of a corneal apparatus for the study of drug permeation across the corneal tissues
is evaluated. The instrument was designed to measure drug transport in living rabbit …
is evaluated. The instrument was designed to measure drug transport in living rabbit …
Minimally invasive spectroscopic system for intraocular drug detection
J Miller, CG Wilson… - Journal of Biomedical …, 2002 - spiedigitallibrary.org
A novel, minimally invasive measurement technique has been developed for the detection of
drugs in the anterior chamber of the eye. Presently there is no satisfactory, real-time …
drugs in the anterior chamber of the eye. Presently there is no satisfactory, real-time …
Spectroscopic detection of a therapeutic drug in the mammalian eye
J Miller, WS Wilson, WK Kek, CG Wilson… - IEEE Journal of …, 2003 - ieeexplore.ieee.org
We have developed a novel and fast ocular spectrometer and demonstrated its ability to
perform real time spectroscopic measurements in the mammalian eye. The instrument …
perform real time spectroscopic measurements in the mammalian eye. The instrument …
Therapeutic Effects of Contact Lens with Continuous Drug Bioavailability on Rabbits
PW Or, C Wu, IT Chong, IKKP Don… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: A novel drug-delivery lens system that provides continuous bioavailability of drug
to the eye is developed. The feasibility of the system is tested by examining the therapeutic …
to the eye is developed. The feasibility of the system is tested by examining the therapeutic …