下一代测序技术在结直肠癌诊疗中的应用.

陈如萍, 刘蕊 - Tianjin Medical Journal, 2020 - search.ebscohost.com
综述 Page 1 天津医药2020 年9 月第48 卷第9 期 下一代测序技术在结直肠癌诊疗中的应用 陈如萍
1,2,刘蕊2△ 摘要:下一代测序(NGS)技术在结直肠癌(CRC)临床诊断及治疗中的潜在应用价值已 …

[HTML][HTML] Clinical application of targeted next generation sequencing for colorectal cancers

Q Fontanges, R De Mendonca, I Salmon… - International journal of …, 2016 - mdpi.com
Promising targeted therapy and personalized medicine are making molecular profiling of
tumours a priority. For colorectal cancer (CRC) patients, international guidelines made RAS …

下一代测序(NGS) 技术的发展及在肿瘤研究的应用

邵向阳, 徐伟文 - 分子诊断与治疗杂志, 2016 - cqvip.com
下一代测序(next-generation sequencing, NGS) 由于高灵敏度, 高通量, 高度自动化等特性,
近年来在疾病的研究和诊断治疗中越来越多地被应用. 下一代测序技术的发展为肿瘤分子生物学 …

Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients

Y Wang, H Liu, Y Hou, X Zhou, L Liang, Z Zhang, H Shi… - Virchows Archiv, 2018 - Springer
Next-generation sequencing (NGS) has become a promising approach for tumor somatic
mutation detection. However, stringent validation is required for its application on clinical …

[HTML][HTML] The clinical versatility of next-generation sequencing in colorectal cancer

KJ Hancock, W Hsu, VS Klimberg - American journal of biomedical …, 2020 - ncbi.nlm.nih.gov
Abstract Next-Generation Sequencing is an evolving technology employed in the field of
cancer biology. This mini review is intended as a brief overview of NGS for the clinical utility …

下一代测序技术的临床应用规范化问题——参考美国医学遗传学与基因组学会行业标准

姜烈君, 陆晓旭, 黄华艺 - 分子诊断与治疗杂志, 2016 - cqvip.com
下一代测序(next generation sequencing, NGS) 技术已经在临床实验室中得到应用.
该技术的发展以及检测规模和应用范围的扩大, 使基因检测成本大大降低. NGS …

新一代测序技术在肿瘤临床中的应用

张濛, 张青云, 徐国宾 - 临床检验杂志, 2014 - cqvip.com
随着测序技术的不断发展, 成本低, 速度快, 通量高的新一代测序(NGS) 技术在肿瘤临床领域显现
出很高的应用价值. 本文对NGS 在肿瘤临床中的应用和研究进行了综述, 主要包括检测胚系突变 …

下一代测序技术在分子诊断中的应用

魏军, 赵志军 - 分子诊断与治疗杂志, 2013 - cqvip.com
DNA 测序是破译人类疾病的一种强大技术, 尤其在癌症方面. 飞速发展的下一代测序(next—
generation sequencing, NGS) 极大降低了测序成本, 并且实现了高通量 …

[HTML][HTML] Application of next-generation sequencing in clinical oncology to advance personalized treatment of cancer

YF Guan, GR Li, RJ Wang, YT Yi, L Yang… - Chinese journal of …, 2012 - ncbi.nlm.nih.gov
With the development and improvement of new sequencing technology, next-generation
sequencing (NGS) has been applied increasingly in cancer genomics research over the …

Early detection of CRC Biomarker matched FFPE DNA and plasma cell-free DNA from CRC patients using a highly sensitive NGS panel

F Chin, V Sundaram, VQ Lam, D Liu - Cancer Research, 2020 - AACR
Background: Patients with later stage colorectal cancer (CRC) exhibit relatively poor
prognosis, and resistance to drug treatment remains an important factor in the shorter …