早期生活压力与诸如创伤后应激障碍, 注意力缺陷/多动症, 精神分裂症以及焦虑或抑郁行为的
精神疾病的高发率有关. 出生后大脑发育的早期阶段, 突触发生, 神经元成熟和胶质细胞分化等 …

The maturation of the nervous system involves multiple dynamic processes that are
regulated both by genetic factors and environmental input. Although some of these …

Early-life stress is associated with a high prevalence of mental illnesses such as post-
traumatic stress disorders, attention-deficit/hyperactivity disorder, schizophrenia, and anxiety …

Stressful experiences during early life (ELS) can affect brain development, thereby exerting
a profound and long-lasting influence on mental development and psychological health. The …

Exposure to stressors in early postnatal life induces long-lasting modifications in brain
function. This plasticity, an essential characteristic of the brain that enables adaptation to the …

Clinical studies have suggested that early-life stress (ELS) increases the risk of
psychopathologies that are strongly associated with dysfunction of dopaminergic …

Evidences suggest the contributive role of early-life stress (ELS) to affective and anxiety
disorders. Chronic exposure to the same stressor may generate habituation, while the …

Abstract Early-life stress (ELS), a complex traumatic stress including abuse, neglect and
bullying during childhood or adolescence, is closely related to the development of …

Adverse early-life experiences, such as poor maternal care, program an abnormal stress
response that may involve an altered balance between excitatory and inhibitory signals …

During early development, environmental challenges set the stage for permanent changes
in the functioning of the pituitary–adrenal stress response. Since these data have been …