Iron is an essential nutrient virtually almost all organisms including human, but at the same
time, it is toxic because its high reactivity to molecular oxygen generates free radicals …

Iron metabolism disorder is an important public health problem both in the United States and
developing world. Iron deficiency cases are over 2 billion worldwide. In theU. S., 9 million …

Iron is an essential nutrient being involved in numerous biological functions including
oxygen transport, ATP generation, and DNA synthesis. On the other hand, excessive iron …

Iron is an essential metal not only in oxygen delivery, but also in cell proliferation and drug
metabolism, while it is a very toxic metal producing reactive oxygen species (ROS). In order …

Iron is an essential trace metal element for maintaining vital functions, and it is involved in
hemoglobin synthesis, redox reaction, enzyme activity, cell proliferation and apoptosis in …

Iron is essential for life, because it is indispensable for several biological reactions such as
oxygen transport, DNA synthesis and cell proliferation, but is toxic if present in excess since …

Iron is an essential micronutrient with important roles in many critical physiological
processes, especially as a structural component of hemoglobin responsible for oxygen …

Iron is an essential cofactor in a variety of cellular processes. Except for a few unusual
bacterial species, iron is indispensable for living organisms. However, free iron is toxic …

Biological iron is necessary for vital functions and also potentially toxic to the organisms.
This dual effect raised the interest of many investigators to study the mechanisms controlling …

Over the intervening years, there has been a great expansion of knowledge about iron
metabolism and its disorders, and it has become obvious that an update of the field is long …