Neurodegenerative diseases are a group of neuronal disorders caused by progressive
neuronal cell death in different regions of the human brain. Alzheimer's disease (AD) and …

Neurodegenerative diseases are a group of neuronal disorders caused by progressive
neuronal cell death in different regions of the human brain. Alzheimer's disease (AD) and …

神经退行性疾病是全球老龄化人口面临的一个重要健康问题, 患者通常表现为认知下降,
运动功能丧失以及痴呆等症状. 神经退行性疾病的发病机制较为复杂, 目前针对该类疾病的治疗 …

Immune responses in the central nervous system (CNS) function as the host's defense
system against pathogens and usually help with repair and regeneration. However, chronic …

Although the precise mechanisms contributing to secondary brain injury following traumatic
brain injury are complex and obscure, a number of studies have demonstrated that …

Abstract NLRP3 (NLRP3: NOD-, LRR-, and pyrin domain-containing protein 3)
inflammasome is the best-described inflammasome that plays a crucial role in the innate …

Neuroinflammatory response is the immune response mechanism of the innate immune
system of the central nervous system. Both primary and secondary injury can activate …

Inflammasomes are multiprotein complexes that trigger the activation of caspases‐1 and
subsequently the maturation of proinflammatory cytokines interleukin‐1β and interleukin‐18 …

Nerve injury and nerve pain are common diseases caused by neuroinflammation.
Numerous studies have shown that the activation of NLRP3 (nod-like receptor family, pyrin …

The central nervous system (CNS) is the most delicate system in human body, with the most
complex structure and function. It is vulnerable to trauma, infection, neurodegeneration and …