[HTML][HTML] Yangqing Chenfei formula attenuates silica-induced pulmonary fibrosis by suppressing activation of fibroblast via regulating PI3K/AKT, JAK/STAT, and Wnt …

F Yang, R Hou, X Liu, Y Tian, Y Bai, J Li, P Zhao - Phytomedicine, 2023 - Elsevier
Abstract Background Yangqing Chenfei formula (YCF) has been demonstrated its clinical
efficiency on silicosis patients. However, the effect of YCF against silicotic fibrosis and its …

Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization

X Tian, Y Wei, R Hou, X Liu, Y Tian, P Zhao, J Li - Chinese Medicine, 2023 - Springer
Abstract Background Yangqing Chenfei formula (YCF) is a traditional Chinese medicine
formula for early-stage silicosis. However, the therapeutic mechanism is unclear. The …

Dihydroquercetin attenuates silica-induced pulmonary fibrosis by inhibiting ferroptosis signaling pathway

L Yuan, Y Sun, N Zhou, W Wu, W Zheng… - Frontiers in …, 2022 - frontiersin.org
Silicosis is a fatal occupational lung disease which currently has no effective treatment.
Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-inflammatory, anti …

[HTML][HTML] Quercetin alleviates pulmonary fibrosis in silicotic mice by inhibiting macrophage transition and TGF-β-Smad2/3 pathway

F Geng, L Zhao, Y Cai, Y Zhao, F Jin, Y Li, T Li… - Current Issues in …, 2023 - mdpi.com
Silicosis is a pulmonary disease caused by the inhalation of silica. There is a lack of early
and effective prevention, diagnosis, and treatment methods, and addressing silicotic fibrosis …

A novel N-arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage …

M Fan, H Xiao, D Song, L Zhu, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Silicosis is one of the potentially fatal occupational diseases characterized by respiratory
dysfunction, chronic interstitial inflammation, and fibrosis, for which treatment options are …

XAV‐939 inhibits epithelial‐mesenchymal transformation in pulmonary fibrosis induced by crystalline silica via the Wnt signaling pathway

Z Lv, H Xu, X Si, S Xu, X Li, N Li, Q Zhou… - Environmental …, 2023 - Wiley Online Library
Silicosis is an occupational lung disease that results from long‐term inhalation of free silica
dust, the expression is sustained inflammation response, fibroblast hyperplasia, and …

[HTML][HTML] Earthworm extract attenuates silica-induced pulmonary fibrosis through Nrf2-dependent mechanisms

J Yang, T Wang, Y Li, W Yao, X Ji, Q Wu, L Han… - Laboratory …, 2016 - Elsevier
Silicosis is an occupational pulmonary fibrosis caused by inhalation of silica (SiO 2) and
there are no ideal drugs to treat this disease. Earthworm extract (EE), a natural nutrient, has …

Dahuang Zhechong Pills Suppress Silicosis Fibrosis Progression via p38 MAPK/TGF‐β1/Smad Pathway In Vitro

LJ Wu, XY He, WX Wang, J Liang… - Evidence‐Based …, 2021 - Wiley Online Library
Background. Dahuang Zhechong pills (DHZCP) is a classic Chinese medicinal prescription
in “Treatise on Cold Pathogenic and Miscellaneous Diseases (Shanghan Zabing Lun),” and …

[HTML][HTML] Baicalin alleviates silica-induced lung inflammation and fibrosis by inhibiting TLR4/NF-κB pathway in rats

Y Zhang, LIU Fang, JIA Qiang, L Zheng… - Physiological …, 2023 - ncbi.nlm.nih.gov
Silicosis is an occupational lung disease caused by inhaling silica dust. The disease is
characterized by early lung inflammation and late irreversible pulmonary fibrosis. Here we …

Metformin attenuates silica-induced pulmonary fibrosis via AMPK signaling

D Cheng, Q Xu, Y Wang, G Li, W Sun, D Ma… - Journal of translational …, 2021 - Springer
Background Silicosis is one of the most common occupational pulmonary fibrosis caused by
respirable silica-based particle exposure, with no ideal drugs at present. Metformin, a …