Injuries to the spinal cord result in permanent disabilities that limit daily life activities. The
main reasons for these poor outcomes are the limited regenerative capacity of central …

Injuries to the spinal cord result in permanent disabilities that limit daily life activities. The
main reasons for these poor outcomes are the limited regenerative capacity of central …

Severe spinal cord injury (SCI) leads to devastating loss of neurological function below the
level of injury and adversely affects multiple body systems. Most basic research on SCI is …

Spinal cord injury is one of the most devastating conditions that affects the central nervous
system. It can lead to permanent disability and there are around two million people affected …

The central nervous system (CNS) has a limited capacity for regeneration after injury. In
spinal cord injury (SCI) patients, total loss of all motor and sensory function occurs below the …

Spinal cord (SC) injury causes serious neurological alterations that importantly disturb the
physical, emotional and economical stability of affected individuals. Damage to the neural …

Acute spinal cord injury initiates a complex cascade of molecular events termed 'secondary
injury', which leads to progressive degeneration ranging from early neuronal apoptosis at …

Neuroprotective therapies in the setting of spinal cord injury offer the advantage of limiting
secondary damage, which is likely more effective than replacing damaged or lost cells. The …

In an effort to develop therapies for promoting neurological recovery after spinal cord injury,
much work has been done to identify the cellular and molecular factors that control axonal …

Introduction Spinal cord injury (SCI) affects 25,000–50,000 people around the world each
year and there is no cure for SCI patients currently. The primary injury damages spinal cord …