天然产物新靶点: 自噬-溶酶体途径(英文)

沈汉明 - 中国药理学与毒理学杂志, 2015 - cqvip.com
Autophagy is an evolutionarily well conserved process in which the cellular components
including damaged subcellular organelles are engulfed in autophagosome and eventually …

天然产物新靶点: 自噬-溶酶体途径

沈汉明 - 中国药理学与毒理学杂志, 2015 - cjpt.magtechjournal.com
Autophagy is an evolutionarily well conserved process in which the cellular components
including damaged subcellular organelles are engulfed in autophagosome and eventually …

[HTML][HTML] New horizon in autophagy research

W Le, Z Qin - Acta Pharmacologica Sinica, 2013 - nature.com
The word autophagy is derived from the Greek roots “auto”(self) and “phagy”(eating) and
broadly refers to the cellular catabolic processes, in which cytoplasmic materials are …

Seeking new anti-cancer agents from autophagy-regulating natural products

F Hua, S Shang, ZW Hu - Journal of Asian natural products …, 2017 - Taylor & Francis
Natural products are an important original source of many widely used drugs, including anti-
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …

自噬在抗肿瘤药物毒性中的作用与机制研究进展

陈剑, 曾艳, 高子正, 胡誉怀, 颜皓, 徐志飞, 罗沛华… - 药学进展, 2022 - pps.cpu.edu.cn
自噬是真核细胞中高度保守的依赖于溶酶体的胞内降解途径, 在众多生理病理过程中发挥重要
作用. 随着对自噬关键基因与信号通路的深入解析, 自噬与抗肿瘤药物毒性之间的关系也逐渐被 …

[HTML][HTML] Application and interpretation of current autophagy inhibitors and activators

Y Yang, L Hu, H Zheng, C Mao, W Hu… - Acta Pharmacologica …, 2013 - nature.com
Autophagy is the major intracellular degradation system, by which cytoplasmic materials are
delivered to and degraded in the lysosome. As a quality control mechanism for cytoplasmic …

Novel pharmacological modulators of autophagy: an updated patent review (2012-2015)

J Ha, J Kim - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
Introduction: Autophagy is a lysosome-dependent degradation pathway that maintains
cellular homeostasis in response to a variety of cellular stresses. Accumulating reports …

Potential therapeutic applications of autophagy

DC Rubinsztein, JE Gestwicki, LO Murphy… - Nature reviews Drug …, 2007 - nature.com
Autophagy is a dynamic process of subcellular degradation, which has recently sparked
great interest as it is now recognized to be involved in various developmental processes and …

Research progress on the anticancer molecular mechanism of targets regulating cell autophagy

T Zhang, J Yu, S Cheng, Y Zhang, C Zhou, J Qin… - Pharmacology, 2023 - karger.com
Background: Autophagy is a lysosome-mediated catabolic process that maintains cell
homeostasis and survival. It occurs not only in normal cells such as cardiac muscle cells …

Seeking new anti-cancer agents from autophagy-regulating natural products.

HF Hua Fang, SS Shang Shuang, HZW Hu ZhuoWei - 2017 - cabidigitallibrary.org
Natural products are an important original source of many widely used drugs, including anti-
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …