Targeting autophagy with natural products as a potential therapeutic approach for cancer
MAA Al-Bari, Y Ito, S Ahmed, N Radwan… - International journal of …, 2021 - mdpi.com
Macro-autophagy (autophagy) is a highly conserved eukaryotic intracellular process of self-
digestion caused by lysosomes on demand, which is upregulated as a survival strategy …
digestion caused by lysosomes on demand, which is upregulated as a survival strategy …
Research progress on the anticancer molecular mechanism of targets regulating cell autophagy
T Zhang, J Yu, S Cheng, Y Zhang, C Zhou, J Qin… - Pharmacology, 2023 - karger.com
Background: Autophagy is a lysosome-mediated catabolic process that maintains cell
homeostasis and survival. It occurs not only in normal cells such as cardiac muscle cells …
homeostasis and survival. It occurs not only in normal cells such as cardiac muscle cells …
New visions on natural products and cancer therapy: autophagy and related regulatory pathways
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …
paying attention to medicinal applications of natural products. There are several …
Phytochemicals as potent modulators of autophagy for cancer therapy
MA Moosavi, A Haghi, M Rahmati, H Taniguchi… - Cancer Letters, 2018 - Elsevier
The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …
diseases, and accordingly universal research efforts have focused on exploring novel …
Molecular insights into the multifunctional role of natural compounds: autophagy modulation and cancer prevention
Autophagy is a vacuolar, lysosomal degradation pathway for injured and damaged protein
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
molecules and organelles in eukaryotic cells, which is controlled by nutrients and stress …
Selective autophagy in cancer: mechanisms, therapeutic implications, and future perspectives
J Liu, Y Wu, S Meng, P Xu, S Li, Y Li, X Hu, L Ouyang… - Molecular cancer, 2024 - Springer
Eukaryotic cells engage in autophagy, an internal process of self-degradation through
lysosomes. Autophagy can be classified as selective or non-selective depending on the way …
lysosomes. Autophagy can be classified as selective or non-selective depending on the way …
[HTML][HTML] Unfolding the role of autophagy in the cancer metabolism
Autophagy is considered an indispensable process that scavenges toxins, recycles complex
macromolecules, and sustains the essential cellular functions. In addition to its …
macromolecules, and sustains the essential cellular functions. In addition to its …
Autophagy modulation as a target for anticancer drug discovery
X Li, H Xu, Y Liu, N An, S Zhao, J Bao - Acta Pharmacologica Sinica, 2013 - nature.com
Autophagy, an evolutionarily conserved catabolic process involving the engulfment and
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
Seeking new anti-cancer agents from autophagy-regulating natural products
F Hua, S Shang, ZW Hu - Journal of Asian natural products …, 2017 - Taylor & Francis
Natural products are an important original source of many widely used drugs, including anti-
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …
Autophagy and its potent modulators from phytochemicals in cancer treatment
CY Sun, QY Zhang, GJ Zheng, B Feng - Cancer chemotherapy and …, 2019 - Springer
Autophagy is a ubiquitous catabolic process by which damaged or harmful intracellular
components are delivered to the lysosomes for self-digestion and recycling. It is critical in …
components are delivered to the lysosomes for self-digestion and recycling. It is critical in …