Objectives Heme chloride (Hemin) is an in vitro purified form of natural heme and an
important raw material for anti-anemia and antitumor drugs. This study aims to analyze the …

Objective To investigate the protective role of heme oxygenase-1 and its reaction product,
carbon monoxide against acute liver injury induced by carbon tetrachloride in rats. Methods …

The cell model of oxidative-stress damage was made successfully by hydrogen peroxide in
human umbilicus vein endothelial cells. The cultured cells were divided into three groups …

Objective To investigate the effects of heme oxygenase 1 inducer hemin on protection of
ischemia-reperfusion injury in rats and its mechanisms. Methods The Langendorff model of …

Primary objective: The purpose of this study was to investigate the effects of heme
oxygenase-1 (HO-1) on astrocyte injury induced by hemin. Research design: Primary …

In the brain, the heme oxygenase (HO) system has been reported to be very active and its
modulation seems to play a crucial role in the pathophysiology of neurodegenerative …

Objective To determine the role of hemoglobin (HB) induced heme oxygenase-1 (HO-1) in
injured lungs caused by limb ischemia-reperfusion (I/R) in rats. Methods A rat model of …

Objective To observe the changes in heme oxygenase-1 (HO-1) expression in lung tissue
with ventilator induced lung injury (VILI) in rats, and to explore the mechanism of preventive …

There is no effective drug for the therapy of acute carbon monoxide (CO) poisoning. The
purpose of the present study was to investigate the potential preventive and therapeutic …

Hemin, an inducer of heme oxygenase‐1 (HO‐1), can enhance the activation of HO‐1. HO‐
1 exhibits a variety of activities, such as anti‐inflammatory, antioxidative, and antiapoptotic …