血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …

Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …

In the last decade, miRNAs have received substantial attention as potential players of
diabetes microvascular complications, affecting the kidney, the retina, and the peripheral …

Diabetic wound healing is an incompletely understood pathophysiological state. It
comprises a range of potentially devastating and common complications of diabetes mellitus …

1050 Arterioscler Thromb Vasc Biol June 2016 unknown role for adipose tissue in
modulating endothelial cell responses in humans. Several of these studies used endothelial …

The development of type-2 diabetes mellitus (T2DM) and its complications is largely due to
the complex interaction between genetic factors and environmental influences, mainly …

Background—Diabetes mellitus impairs endothelial cell (EC) function and postischemic
reparative neovascularization by molecular mechanisms that are not fully understood …

Diabetes mellitus is usually accompanied by nephropathy, retinopathy, and neuropathy as
microvascular complications. MicroRNAs (miRNAs) can affect the kidney, retina, and …

Diabetes is the most prevalent metabolic disturbance disease and has been regarded
globally as one of the principal causes of mortality. Diabetes is accompanied by several …

Abstract Both Type 1 and Type 2 diabetes can lead to debilitating microvascular
complications such as retinopathy, nephropathy and neuropathy, as well as macrovascular …