Psoriasis is a chronic and multifactorial skin disease affecting B2% of the population
worldwide (Griffiths and Barker, 2007). There is a higher risk of psoriasis among …

Ten genome-wide scans have been conducted over the past few years in the search for
psoriasis susceptibility genes, but only one potential susceptibility region has been …

MORE THAN 25 years of accu-mulating evidence strongly implicates the immune system in
the pathogenesis of psoriasis, including both acquired immunity (T cells) and innate host …

Psoriasis is a heterogeneous disease with seven major psoriasis susceptibility loci reported
so far on chromosomes 1p, 1q, 3q, 4q, 6p, 17q, and 19p, respectively. To investigate the …

Although researchers have made major advances through the discovery of more than 40
genetic loci associated with psoriasis by genome-wide association studies (GWAS), this only …

Psoriasis is a common and debilitating disease of the skin, nails, and joints, with an
acknowledged but complex genetic basis. Early genome-wide linkage studies of psoriasis …

Theme issue: Psoriasis loci. Despite the complex correlation structure across the MHC due
to extensive linkage disequilibrium (Box 1)(16), HLA-C* 06: 02 is now confidently …

Objective: To investigate three suggested psoriasis susceptibility loci at 2p22. 3-11.2, 13q21-
32, and 17q22-25.3 in a Chinese population. Background and methods: Psoriasis is a …

Psoriasis is a common autoimmune and hyperproliferative skin disease, characterized by
thick, silvery scale patches. It usually occurs within the third decade of life, with a prevalence …

Psoriasis is a chronic, inflammatory, immune-mediated skin condition with a prevalence of 0–
11.8% across the world. It is associated with a number of cardiovascular, metabolic, and …