Background Pituitary tumors are common lesions, and they represent the second most
frequent primary brain tumor. Their classification has undergone several changes over time …

The classification of pituitary tumors is a dynamic area that changes with advances in cell
biology that provide a deeper insight and clearer understanding of cell lineages and …

The 4th edition of the World Health Organization (WHO) classification of endocrine tumors
has been recently released. In this new edition, major changes are recommended in several …

Objective Pituitary tumours comprise a pathologically and clinically diverse group of
neoplasms. Classification frameworks have changed dramatically in the past two decades …

Pituitary tumors are very complex and heterogeneous and have a very wide range of
proliferative and aggressive behaviors, and how to define and classify these tumors remains …

This review focuses on discussing the main changes on the upcoming fourth edition of the
WHO Classification of Tumors of the Pituitary Gland emphasizing histopathological and …

Pituitary adenomas constitute approximately 15% of all intra-cranial neoplasms. The
majority of pituitary tumors are adenomas, which are benign and noninvasive (confined to …

WHO classification of pituitary adenomas was revised in 2017. The two major and significant
changes are discussed.(1) The new classification focuses on adenohypophysial-cell lineage …

Pituitary adenomas are common neoplasms. Their classification is based upon size,
invasion of adjacent structures, sporadic or familial cases, biochemical activity, clinical …

Pituitary tumors are common and exhibit a wide spectrum of hormonal, proliferative and
invasive behaviors. Traditional classifications consider them malignant only when they …