Systemic inflammation is often accompanied by adaptive responses mediated by the central
nervous system, such as lack of motivation and attention, fatigue, malaise, irritation or even …

Systemic inflammation is often accompanied by adaptive responses mediated by the central
nervous system, such as lack of motivation and attention, fatigue, malaise, irritation or even …

Microglial cells constantly surveil the cerebral microenvironment and become activated
following injury and disease to mediate inflammatory responses. The nucleotide-binding …

摘要: NLRP3 通过改变免疫反应在各种疾病中发挥着关键作用. 免疫系统和神经系统之间存在着
诸多联系, 故其在中枢和外周神经病理学中也起着关键作用. 在周围神经损伤后 …

Microglial inflammation driven by the NACHT, LRR and PYD domain‐containing protein 3
(NLRP3) inflammasome contributes to brain disease and is a therapeutic target. Most …

Infection, predominantly induced by gram-negative bacteria, is a critical health problem and
a leading cause of death worldwide. Advance of techniques, such as antibiotics and life …

认知功能障碍作为一种常见的神经系统疾病, 以认知减退, 记忆力和注意力障碍为主要临床表现,
严重影响患者的生存质量, 是当前医学研究的热点和难点. 认知功能障碍的病因及发病机制复杂 …

Acute cerebral dysfunction is a pathological state common in severe infections and a pivotal
determinant of long-term cognitive outcomes. Current evidence indicates that a loss of …

Neurodegenerative diseases are a group of neuronal disorders caused by progressive
neuronal cell death in different regions of the human brain. Alzheimer's disease (AD) and …

Inflammation in the brain accompanies several high-impact neurological diseases including
multiple sclerosis (MS), stroke, and Alzheimer's disease. Neuroinflammation is sterile, as …