[PDF][PDF] The Journalo 暴避mmtt 2V Nod 1, Accelerates Atherogenesis in Apoe Activation of an Innate Immune Receptor

S Kanno, H Nishio, T Tanaka, SY Onimaru, H Kono… - 2015 - mhlw-grants.niph.go.jp
Atherosclerosis is essentially a vascular inflammatory process in the presence of an excess
amount of lipid. We have recently reported that oral administration of a nucleotide-binding …

Activation of an innate immune receptor, Nod1, accelerates atherogenesis in Apoe−/− mice

S Kanno, H Nishio, T Tanaka, Y Motomura… - The Journal of …, 2015 - journals.aai.org
Atherosclerosis is essentially a vascular inflammatory process in the presence of an excess
amount of lipid. We have recently reported that oral administration of a nucleotide-binding …

Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid‐rich necrotic cores in hypercholesterolemic mice

ME Johansson, XY Zhang, K Edfeldt… - European journal of …, 2014 - Wiley Online Library
Atherosclerosis is an inflammatory disease associated with the activation of innate immune
TLRs and nucleotide‐binding oligomerization domain‐containing protein (NOD)‐like …

NOD1-OXLDLS-VCAM1 axis controls leukocyte recruitment to the athero-prone vasculature enhancing atherosclerosis disease

BVF García, LB Gomar, SG Ramos - Atherosclerosis, 2020 - atherosclerosis-journal.com
Methods: Pro-atherogenic Apoe-/-Nod1-/-against Apoe-/-mice treated with high fat diet (3
weeks) were phenotypically and physiologically characterized. Human coronary arteries …

The role of innate immune receptor nod2 in atherosclerosis

XY Zhang, M Johansson, A Lundberg… - …, 2014 - atherosclerosis-journal.com
Objectives: Atherosclerosis is a chronic inflammatory disease, involving activation of innate
and adaptive immunity. Innate immunity is triggered by signaling through pattern recognition …

Deletion of Nod1 prevents atherosclerosis development in Apoe-deficient mice

M Paz-García, L Boscá, M Fernández-Velasco… - 2015 - digital.csic.es
Atherosclerosis is a complex and chronic infl ammatory disease characterized by the
development of lipid-rich plaques in large arteries. Emerging evidence suggest a link …

Genetic inactivation of the innate immune receptor NOD1 prevents vascular inflammation linked to atherosclerosis

S Gonzalez-Ramos, M Paz-García… - …, 2017 - atherosclerosis-journal.com
Aim: On the basis of the background relating the intracellular pattern-recognition sensor
called nucleotide-binding oligomerization domain-containing protein 1 (NOD1) and …

NOD2-mediated innate immune signaling regulates the eicosanoids in atherosclerosis

HQ Liu, XY Zhang, K Edfeldt, MO Nijhuis… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—The activity of eicosanoid pathways is critical to the inflammatory and immune
responses that are associated with the progression of atherosclerosis. Yet, the signals that …

Nod1 ligands induce site-specific vascular inflammation

H Nishio, S Kanno, S Onoyama, K Ikeda… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—The goal of this study was to investigate the effects of stimulants for a nucleotide-
binding domain, leucine-rich repeat-containing (NLR) protein family on human artery …

Impact of the nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 on experimental atherosclerosis and lipid metabolism

A Vlacil, H Schütt, J Schütt, R Oberoi… - …, 2018 - atherosclerosis-journal.com
Aim: Atherosclerosis is crucially fueled by inflammatory pathways including pattern
recognition receptor-related signaling of the innate immunity. However, the impact of the …