… that occurs in sepsis, and explain why many previous sepsis trials which were … use in sepsis.
We hypothesise that immunoadjuvant therapy represents the next major advance in sepsis. …

… sepsis. Therefore pharmacologic stimulation of vagus nerve to release Ach may prove better
therapeutic approach to treat bacterial sepsis. … response responsible for sepsis by binding to …

… the different phases of septic shock, at least … septic shock combined with the blockade of
endothelin receptors at later stages appear feasible and a novel strategy for the therapy of septic …

… Severe sepsis leading to shock is the principal cause of death in … therapeutic development.
This article discusses selected pathophysiological mechanisms that might yield to therapeutic …

… Despite advances in management, sepsis and septic shock still … and therapeutic approaches
of sepsis and septic shock. … sepsis or septic shock because the antimicrobial therapy can …

… Immune suppression in sepsis has been the object of more intensive … therapeutic approaches
for septic patients [30-32]. In this respect, the initial hyperinflammatory response in sepsis …

… , therapy-guidance and outcome prediction of sepsis. The therapy of septic patients …
diagnostic substances, biomarker-guided therapy approaches should gain further attention. …

… of sepsis immune pathophysiology, to update the choice of therapeutic approaches targeting
different immunological mechanisms in the course of sepsis and septic shock, and to call …

… and sepsis severity. In this review, we highlight the crucial role of the glycocalyx in sepsis
as a … serving as hopeful therapeutic targets in sepsis‐associated multiple organ failures. …

… clinically benefitted substantially from therapeutic approaches derived from reductionist
animal modeling including checkpoint proteins, designer T-cells, to name a few [Citation43–45]. …