Apoptosis in sepsis: a new target for therapeutic exploration
C Oberholzer, A Oberholzer, M Clare-Salzler… - The FASEB …, 2001 - Wiley Online Library
… lead to caspasemediated apoptosis, represent an attractive therapeutic target for the septic
… apoptotic pathways in sepsis syndrome and propose several potential therapeutic targets. …
… apoptotic pathways in sepsis syndrome and propose several potential therapeutic targets. …
Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets
A Ayala, M Perl, F Venet, J Lomas-Neira… - Current …, 2008 - ingentaconnect.com
… the development of sepsis if we are to optimize these present clinical therapies and/or develop
… last decade, emerging evidence in sepsis research suggests that apoptosis in a variety of …
… last decade, emerging evidence in sepsis research suggests that apoptosis in a variety of …
[HTML][HTML] Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis
C Cao, M Yu, Y Chai - Cell death & disease, 2019 - nature.com
… Thus manipulating apoptosis could be a new therapeutic approach in sepsis. Further,
exploring potential therapeutic targets related to apoptosis will be valuable in reversing …
exploring potential therapeutic targets related to apoptosis will be valuable in reversing …
Insights into sepsis therapeutic design based on the apoptotic death pathway
Y Hattori, K Takano, H Teramae… - Journal of …, 2010 - jstage.jst.go.jp
… therapy may offer a unique alternative sepsis treatment to shorten the apoptotic arm of sepsis,
revealing a number of targets within the apoptotic … /or adjuvant therapies that would have a …
revealing a number of targets within the apoptotic … /or adjuvant therapies that would have a …
Novel therapeutic targets for sepsis: regulation of exaggerated inflammatory responses
… Herein, we review the therapeutic … and modalities for sepsis, which is under
experimental … The accumulation of apoptotic cells is one of the major hallmarks of sepsis. …
experimental … The accumulation of apoptotic cells is one of the major hallmarks of sepsis. …
Considering immunomodulatory therapies in the septic patient: should apoptosis be a potential therapeutic target?
A Oberholzer, C Oberholzer, RM Minter, LL Moldawer - Immunology Letters, 2001 - Elsevier
… with sepsis syndrome will likely require multi-modal therapies … for septic patients at present,
further exploration of this clinical … with sepsis will require multiple therapeutic approaches, …
further exploration of this clinical … with sepsis will require multiple therapeutic approaches, …
Emerging therapeutic targets for sepsis
EW Tindal, BE Armstead, SF Monaghan… - … on therapeutic …, 2021 - Taylor & Francis
… Renewed exploration of the therapeutic utility of this pathway has focused on thrombomodulin,
… Probiotic treated subjects also exhibited levels of colonic epithelial apoptosis and cellular …
… Probiotic treated subjects also exhibited levels of colonic epithelial apoptosis and cellular …
[HTML][HTML] Signaling pathways and intervention therapies in sepsis
Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
… In a tentative exploration of hospital-treated sepsis data obtained from high-income … via
suppressing myocardial and serum inflammatory cytokines, apoptosis, and pyroptosis. STING-…
suppressing myocardial and serum inflammatory cytokines, apoptosis, and pyroptosis. STING-…
Induction of apoptosis in sepsis: cell suicide may be beneficial
SJ Finney, TW Evans - Critical Care Medicine, 2002 - journals.lww.com
… to explore this issue further. Second, the data highlight the therapeutic potential of manipulating
apoptosis in sepsis, although there are, as yet, no effective tools available to explore this …
apoptosis in sepsis, although there are, as yet, no effective tools available to explore this …
[HTML][HTML] The role and mechanism of pyroptosis and potential therapeutic targets in sepsis: a review
X Zheng, W Chen, F Gong, Y Chen, E Chen - Frontiers in immunology, 2021 - frontiersin.org
… to explore their therapeutic … -apoptotic and anti-inflammatory effects by inhibiting IL-1β and
IL-18 release in the CLP rat model and showed significant therapeutic effects against sepsis (…
IL-18 release in the CLP rat model and showed significant therapeutic effects against sepsis (…
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