Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

MG Murer, Q Yan, R Raisman-Vozari - Progress in neurobiology, 2001 - Elsevier
… distribution in the human brain, and the modifications of BDNF expression which occur in
the brain of individuals with Alzheimer’s disease and Parkinson’s disease. Our knowledge …

A century of Alzheimer's disease

M Goedert, MG Spillantini - science, 2006 - science.org
… (88), which suggests that imaging with PIB can detect clinical and preclinical disease. In
the future, it may also become possible to image tau deposits in the living human brain. …

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… DNA methylation (5-methylcytosine [5mC]) is one of several epigenetic markers altered
in Alzheimer's disease (AD) brain. More recently, attention has been given to DNA …

Lipid alterations in lipid rafts from Alzheimer's disease human brain cortex

V Martín, N Fabelo, G Santpere, B Puig… - … of Alzheimer's …, 2010 - content.iospress.com
… of human frontal brain cortex from normal and Alzheimer’s disease (AD) and characterized
their biochemical lipid composition. The results revealed that lipid rafts from AD brains exhibit …

Cholinesterases: new roles in brain function and in Alzheimer's disease

E Giacobini - Neurochemical research, 2003 - Springer
… The brain of mammals contains two major forms of cholinesterases: acetylcholinesterase (…
mammalian brain, which makes the function of BuChE of difficult interpretation. In human brain

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

S Muraoka, AM DeLeo, MK Sethi… - Alzheimer's & …, 2020 - Wiley Online Library
Alzheimer's disease (AD) and control (CTRL)brain tissues: A, Schematic of extracellular
vesicle isolation protocol from human frozen brain … B, Left: particle numbers of brain-derived EV …

[HTML][HTML] Meta-analysis of the Alzheimer's disease human brain transcriptome and functional dissection in mouse models

YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal… - Cell reports, 2020 - cell.com
… the human brain transcriptome in Alzheimer's disease (AD), based on meta-analysis of
differential gene expression in 2,114 postmortem samples. We discover 30 brain … with 251 brain

Alzheimer's disease

P Scheltens, K Blennow, MMB Breteler, B De Strooper… - The Lancet, 2016 - thelancet.com
… lifestyle interventions targeting general brain health to jointly combat the disease. In this … In
panel 1, we describe two cases, which show the range of Alzheimer's disease in terms of age …

[HTML][HTML] Lifespan changes of the human brain in Alzheimer's disease

P Coupé, JV Manjón, E Lanuza, G Catheline - Scientific reports, 2019 - nature.com
… Recently, we used BigData approach to propose an analysis of brain trajectory across the …
the human brain in AD. To this end, we propose to build an extrapolated model of AD for brain

Alzheimer's disease

CL Masters, R Bateman, K Blennow… - Nature reviews disease …, 2015 - nature.com
… in the brains of patients with Alzheimer's disease. APOE is … found in the brain tissue of
patients with Alzheimer's disease. … or contributing factor for Alzheimer's disease by acting as a …