Patterns of brain activation in people at risk for Alzheimer's disease

SY Bookheimer, MH Strojwas, MS Cohen… - New England journal …, 2000 - Mass Medical Soc
… between brain responses to tasks requiring memory and the genetic risk of Alzheimer's
disease, … magnetic resonance imaging (MRI) of the brain in older persons with intact cognition. …

Altered brain activation in cognitively intact individuals at high risk for Alzheimer's disease

CD Smith, AH Andersen, RJ Kryscio, FA Schmitt… - Neurology, 1999 - AAN Enterprises
… This study examined group differences in brain activation but did not have the power to
assess individual contributions to these differences. It is important to note that each individual’s …

Different patterns of brain activation in normal aging and Alzheimer's disease from cognitional sight: meta analysis using activation likelihood estimation

S Sadigh-Eteghad, A Majdi, M Farhoudi… - Journal of the …, 2014 - Elsevier
Alzheimer disease (AD) is a chronic neurological disease, frequently affecting cognitional
functions. Recently, a large body of neuro-imaging studies have aimed at finding reliable …

Lifespan brain activity, β-amyloid, and Alzheimer's disease

WJ Jagust, EC Mormino - Trends in cognitive sciences, 2011 - cell.com
… with PIB and brain activation using fMRI in people with genetic risks for sporadic AD and
in older individuals provide supportive evidence that lifelong structural and functional brain

Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease

S Rombouts, F Barkhof, CS Van Meel… - Journal of Neurology …, 2002 - jnnp.bmj.com
… to a large Alzheimer’s disease population. However, we did find an effect on brain
activation in memory related areas in this specific Alzheimer’s disease cohort when performing …

Specificity of brain activation patterns in people at genetic risk for Alzheimer disease

AC Burggren, GW Small, FW Sabb… - The American journal of …, 2002 - Elsevier
… the control condition separately, we can observe the gradual increase in brain activation
as task difficulty increases. Increased fMRI activation in the left superior parietal lobule and …

Specific and disease stage-dependent episodic memory-related brain activation patterns in Alzheimer's disease: a coordinate-based meta-analysis

N Nellessen, C Rottschy, SB Eickhoff… - Brain Structure and …, 2015 - Springer
… attenuated right hippocampal activation during retrieval tasks. … stronger activation of the
precuneus and reduced activation of … probably disease stage-dependent brain activation pattern …

Large-scale functional brain network abnormalities in Alzheimer's disease: insights from functional neuroimaging

BC Dickerson, RA Sperling - Behavioural neurology, 2009 - content.iospress.com
… Alternatively, increased regional brain activation may be a marker of the pathophysiologic
process of AD itself, such as aberrant sprouting of cholinergic fibers [49] or inefficiency in …

Brain imaging in the study of Alzheimer's disease

EM Reiman, WJ Jagust - Neuroimage, 2012 - Elsevier
… Studies of brain activation and the resting state have been informative in application to
fundamental questions of disease pathogenesis that are discussed in greater detail below. …

Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairment

SC Johnson, TW Schmitz, CH Moritz, ME Meyerand… - Neurobiology of …, 2006 - Elsevier
This study examined the functionality of the medial temporal lobe (MTL) and posterior cingulate
(PC) in mild cognitive impairment amnestic type (MCI), a syndrome that puts patients at …