… brain, neuromelanin appears to play a functional role to protect neurons from oxidative load
but we have shown that in the Parkinson’s disease brain … , even early in the disease process. …

… alterations in other metal ions occurring in brain in Parkinson's disease. J Neurochem
1989:52:… Selective increase of iron in substantia nigra zona compacta of parkinsonian brains. J …

… The clinical signs of Parkinson's disease (PD) result from the destruction of the midbrain
dopamine projection from the substantia nigra to the striatum and the loss of dopamine …

… brain tissue structure due to neurological diseases. The main purpose of this study was to
investigate whether DTI signals measured from brain regions … analyzed whole-brain DTI data …

… Cluster-based QSM group statistics (n = 25 Parkinson's disease patients versus n = 50
elderly controls) for the contrast age-corrected QSM greater in Parkinson's disease than in …

… disorders that result clinically difficult to differentiate from idiopathic Parkinson's Disease (PD)
particularly in the early stages of the diseases, when the clinical typical signs are not …

… brain region are crucial for disease progression. Recent in vitro studies, however, have
suggested that activation of microglia and subsequently astrocytes via mediators released by …

… regions of interest and other brain regions. There are several anatomically separated brain
regions that … Functional communication between these brain regions plays a pivotal role in …

… neural activity characteristic of Parkinson's disease. In a … patients with levodopa-responsive
Parkinson's disease. The nuclei … this region of the thalamus in idiopathic Parkinson's disease, …

… Motor impairment represents the main clinical feature of Parkinson's disease (PD). … inhibition
(Go/NoGO-task) to investigate brain activations in 13 patients with early PD in comparison …