Neuroinflammation in Parkinson's disease

EC Hirsch, S Vyas, S Hunot - Parkinsonism & related disorders, 2012 - Elsevier
… pathophysiology of Parkinson’s disease (PD). Furthermore, post mortem studies confirm
the involvement of innate as well as adaptive immunity in the affected brain regions in patients …

Parkinson disease

W Poewe, K Seppi, CM Tanner, GM Halliday… - Nature reviews Disease …, 2017 - nature.com
… of the brain is not a feature of Parkinson disease, rather neuronal degeneration occurs in
only certain types of neurons within particular brain regions. In early-stage disease, loss of …

[HTML][HTML] Parkinson's disease: Is it a consequence of human brain evolution?

NJ Diederich, DJ Surmeier, T Uchihara… - Movement …, 2019 - ncbi.nlm.nih.gov
… PD Is an Exclusively Human Disease Although experimental lesions to the dopaminergic
system lead to Parkinson's disease (PD)like motor symptoms in vertebrates extending from …

Imaging in Parkinson's disease: the role of monoamines in behavior

DJ Brooks, P Piccini - Biological psychiatry, 2006 - Elsevier
Parkinson’s disease patients. PET, positron emission tomography; UPDRS, Unified Parkinson
Disease Rating Scale; rCBF, regional … (61%) Unified Parkinson Disease Rating Scale (…

Genetics of Parkinson's disease

CM Lill - Molecular and cellular probes, 2016 - Elsevier
… As relevant brain tissue is difficult to … brain diseases. Accordingly, no “epigenome-wide
association study” (EWAS) in pathophysiologically relevant brain regions of Parkinson's disease

Oxidative stress and Parkinson's disease

P Jenner - Handbook of clinical neurology, 2007 - Elsevier
… nitrative stress occur in Parkinson's disease is not in question. … pathological picture in
Parkinson's disease, in contrast, … also occurring in the brain in Parkinson's disease is a keen area …

Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls

EJ Burton, IG McKeith, DJ Burn, ED Williams… - Brain, 2004 - academic.oup.com
… 3 Grey matter volume loss in PDD relative to Parkinson's disease, accounting for differences
in head size (P < 0.001 uncorrected). Atrophy was observed in the occipital lobe bilaterally, …

Parkinson's disease patients show reduced corticalsubcortical sensorimotor connectivity

M Sharman, R Valabregue, V Perlbarg… - Movement …, 2013 - Wiley Online Library
brain structures, particularly those in the sensorimotor network, is a hallmark of Parkinson's
disease … affects connectivity within this and other brain networks remains to be investigated. …

Neuroimaging of brain changes associated with cognitive impairment in Parkinson's disease

L Christopher, AP Strafella - Journal of neuropsychology, 2013 - Wiley Online Library
… Functional MRI and H 2 15 O PET has also revealed that Parkinson's disease patients
recruit different brain networks and show altered patterns of activation in cortico-striatal circuitry …

Research in motion: the enigma of Parkinson's disease pathology spread

P Brundin, JY Li, JL Holton, O Lindvall… - Nature Reviews …, 2008 - nature.com
… Neuropathological changes in Parkinson's disease progress … into the brains of patients with
Parkinson's disease. Two of … host neurons in the diseased brains. According to these studies, …