… characterized by resistance to multiple cytotoxic drugs with different … cancer cells already
reveal resistance to drugs at initial exposure to treatment, while in acquired MDR the resistance …

… of therapeutic resistance and metastasis is a major challenge with current breast cancer (BC) …
that a subpopulation of cancer stem cells (CSCs) contribute to the cancer therapeutic …

… resistance and innate Herceptin resistance. In this article, we demonstrate Herceptin resistance
developed in cell … In addition, we address the mechanism of drug resistance given the …

… for cancer relapse. These tumorigenic cancer cells can be isolated from breast cancer biopsies
… In this study, we aimed to test directly in human breast cancers the effect of conventional …

… breast cancer resistance protein (BCRP) is involved in in vitro multidrug resistance and was
first identified in the breast cancer cell … resistance of breast cancer to anthracycline treatment. …

… discovered by three groups, and respectively named breast cancer resistance protein (BCRP
[ 1 ]), ABC in placenta (ABCP [ 2 ]) and mitoxantrone-resistance protein (MXR [ 3 ]). This …

… /AdrVp cells relative to parental MCF-7 cells… breast cancer resistance protein (BCRP).
Enforced expression of the full-length BCRP cDNA in MCF-7 breast cancer cells confers resistance …

… growth rate regularly occur in drug-resistant breast cancer cells. Although we do not know
… drug resistance. These phenotypic changes in drug-resistant human breast cancer cells …

… of the MCF-7 breast cancer cell line and of its multidrug resistant variant (MDR-MCF-… cell
types as compared to the organization of cells cultured as monolayers. The nature of the cellular …

… Cancer cell resistance to therapeutics can result from acquired or de novo-mediated factors.
… breast cancer cell culture models to elucidate de novo doxorubicin resistance mechanisms. …