… Cellular proliferation and ER functionality We initially confirmed that human breast cancer
cells adapt to long-term estrogen … of exogenous estrogen. Figure 1A demonstrates that LTED …

… and proliferation markers in primary and recurrent breast cancer. PNAS 98 … of estrogen
receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor…

… in ER-negative lung cancer cells (14). In this study, we show for the first time that estrogen
activated the PI3K-Akt pathway in breast cancer cells lacking expression of the known ERs. …

… O Evidence presented in this report shows that most ER-positive breast cancer cells are
present as infiltrating tumor cells, and are rarely found in the intraductal noninvasive …

… with breast cancer (BC), the two major endocrine therapies (ET) available are directed at
blocking estrogen receptors (ERs) on cancer cells (selective estrogen receptor modulators), or …

… The discovery of the estrogen receptor (ER) provided us not … target for the treatment of
hormone-dependent breast cancer with … , and treatment of the disease, which is complicated by …

… proliferation of breast cancer cells. We found that proliferation of ER + but not ER − breast
cancer cell lines … Our results show that MYB is an effector of estrogen/ER signaling and provide …

… increased GPR30 expression and ERα-positive status. We therefore examined GPR30 in
estrogenic activities in ER-positive MCF-7 breast cancer cells using G-1 and diethylstilbestrol (…

… of estradiol and various estrogen agonists and/or antagonists using a number of breast cancer
cell lines (both ER-positive … of breast cancer cells by studying ERβ isoform expression in …

… response of these cell lines to long-term estrogen deprivation. … present in ER-positive,
estrogen-dependent breast cancer cells. This … cell populations of clinically observed breast cancer. …