Extracellular matrix in angiogenesis: dynamic structures with translational potential
SA Eming, JA Hubbell - Experimental dermatology, 2011 - Wiley Online Library
… We will focus on the interaction of growth factors with extracellular matrix (ECM) components
during the formation of vascular structures in health and disease. Finally, this article will …
during the formation of vascular structures in health and disease. Finally, this article will …
Cell–extracellular matrix mechanobiology: forceful tools and emerging needs for basic and translational research
… mechanical microenvironment as well as the resulting phenotypic changes have great
potential to shape future basic research as well as provide a basis for translational applications. …
potential to shape future basic research as well as provide a basis for translational applications. …
Extracellular matrix in intervertebral disc: basic and translational implications
S Zhang, W Liu, S Chen, B Wang, P Wang, B Hu… - Cell and Tissue …, 2022 - Springer
… In healthy mature IVD tissues, extracellular matrix (ECM) complex possesses favorable …
ECM within the IVD provides new insight into potential IVD regeneration strategies. Natural ECM …
ECM within the IVD provides new insight into potential IVD regeneration strategies. Natural ECM …
Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials
MC Lampi, CA Reinhart-King - Science translational medicine, 2018 - science.org
… We describe drug development efforts and challenges of individual cellular targets, as
well as the translational potential of available drugs, preclinical studies, and clinical trials. …
well as the translational potential of available drugs, preclinical studies, and clinical trials. …
The extracellular matrix at a glance
C Frantz, KM Stewart, VM Weaver - Journal of cell science, 2010 - journals.biologists.com
The extracellular matrix (ECM) is the noncellular component present within all tissues and …
are subjected to a myriad of post-translational modifications. Through these physical and …
are subjected to a myriad of post-translational modifications. Through these physical and …
Translational control of the fibroblast-extracellular matrix association: an application to pulmonary fibrosis
RS Nho, V Polunovsky - Translation, 2013 - Taylor & Francis
… and relentless accumulation of extracellular matrix (ECM). … of the eIF4F-mediated translational
apparatus is an important … In order to find potential therapeutic targets that are effective …
apparatus is an important … In order to find potential therapeutic targets that are effective …
Post-translational modifications of the extracellular matrix are key events in cancer progression: opportunities for biochemical marker development
… the potential usefulness of a novel class of biochemical markers, designated neoepitopes.
Neoepitopes are post-translational … by cancer-associated extracellular matrix (ECM) proteins. …
Neoepitopes are post-translational … by cancer-associated extracellular matrix (ECM) proteins. …
Extracellular matrix molecules: potential targets in pharmacotherapy
H Järveläinen, A Sainio, M Koulu, TN Wight… - Pharmacological …, 2009 - ASPET
The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …
[HTML][HTML] The extracellular matrix: Tools and insights for the “omics” era
The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization and …
provides mechanical and chemical cues that orchestrate cellular and tissue organization and …
[HTML][HTML] The biomimetic extracellular matrix: a therapeutic tool for breast cancer research
M Tamayo-Angorrilla, JL de Andrés, G Jiménez… - Translational …, 2022 - Elsevier
… Nevertheless, despite the remarkable potential, the rational design of these biomaterials …
The dECMs not only represent a promising potential for regenerative medicine, but also these …
The dECMs not only represent a promising potential for regenerative medicine, but also these …
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