Expression of interstitial collagenase (matrix metalloproteinase-I) is related to the activity of …
matrix metalloproteinase-1 by silver staining for the integrity of the fibrillar extracellular matrix …

… metalloproteinase was identified as human interstitial collagenase (matrix metalloproteinase-1),
an … has heretofore been believed to be the extracellular matrix molecule, collagen. The …

… The results presented in this report demonstrate that interstitial collagenase can promote
the activation of progelatinase A. This is accomplished by the cleavage of a single peptide …

… Most of this degradation is mediated by matrix metalloproteinases (MMPs), a family of … of
the interstitial collagenases in cancer. A consistent theme is that the collagenases are probably …

… -2, free of tissue inhibitors of metalloproteinases (TIMPs) are … interstitial collagenases.
MMP-2 cleaves at the same Gly-Ile/Leu bond in the collagen α chains as interstitial collagenases …

… are enzymes that degrade extracellular matrix components and have been implicated in …
of interstitial collagenase (matrix metalloproteinase 1 [MMP-1]), a major collagenase. …

… metalloproteases (Jiang and Bond, 1992; Bode et al., 1993). Crystal structures of the catalytic
domains of interstitial collagenase (… Collagenases also contain an additional structural zinc …

… proteolytic enzymes termed the matrix metalloproteinases (MMPs). … was performed to localize
interstitial collagenase protein and … Collagenase-1 protein and mRNA were expressed by …

… The roles of type IV collagenase/gelatinase (MMP-2 and … about the pathological role of
interstitial collagenase (MMP-1), … activity of interstitial collagenase and type IV collagenase at the …

… One mechanism for this might be the release by plaque cells of matrix-degrading proteases,
such as interstitial collagenase (matrix metalloproteinase-1, MMP-1), which degrades two …