Low-intensity pulsed ultrasound inhibits messenger RNA expression of matrix metalloproteinase-13 induced by interleukin-1β in chondrocytes in an intensity …

A Ito, T Aoyama, S Yamaguchi, X Zhang… - Ultrasound in medicine …, 2012 - Elsevier
Matrix metalloproteinase (MMP)13 mRNA expression in rat chondrocytes (a) 1 h and (b) 3
h after low-intensity pulsed ultrasound (LIPUS) stimulation at an intensity of 30 mW/cm 2 for 20 …

Effect of low-intensity pulsed ultrasound on MMP-13 and MAPKs signaling pathway in rabbit knee osteoarthritis

X Li, J Li, K Cheng, Q Lin, D Wang, H Zhang… - Cell biochemistry and …, 2011 - Springer
Matrix metalloproteinases (MMPs) are the most important proteolytic system for the degradation
of extracellular matrix [7]. MMP-13 (collagenase-3) can be produced by human cartilage …

[HTML][HTML] Effect of low intensity pulsed ultrasound on expression of TIMP-2 in serum and expression of mmp-13 in articular cartilage of rabbits with knee osteoarthritis

JB Ji, XF Li, L Liu, GZ Wang, XF Yan - Asian Pacific journal of tropical …, 2015 - Elsevier
pulsed ultrasound (LIPUS) on the expression of tissue inhibitor of metalloproteinase-2 (TIMP…
The frequency of low intensity pulsed ultrasound (LIPUS) is usually 1–3 MHz, with the …

Low-intensity pulsed ultrasound affects chondrocyte extracellular matrix production via an integrin-mediated p38 MAPK signaling pathway

P Xia, S Ren, Q Lin, K Cheng, S Shen, M Gao… - Ultrasound in medicine & …, 2015 - Elsevier
Matrix metalloproteinases (MMPs) are the most important proteolytic enzymes in the
degradation of ECM, and MMP-13 is the most effective enzyme for degrading type II collagen (Blain …

Low-intensity pulsed ultrasound stimulates matrix metabolism of human annulus fibrosus cells mediated by transforming growth factor β 1 and extracellular signal …

MH Chen, JS Sun, SY Liao, PA Tai, TC Li… - Connective Tissue …, 2015 - Taylor & Francis
… Low-intensity pulsed ultrasound (LIPUS) has positive … and matrix metabolism. Cell viability,
synthesis of collagen and glycosaminoglycan (GAG), expression of matrix metalloproteinases

The effects of low-intensity pulsed ultrasound and nanomagnet applications on the expressions of MMP-13 and MAPKs in rabbit knee osteoarthritis

X Li, Q Lin, D Wang, Y Dai, K Cheng… - … of Nanoscience and …, 2013 - ingentaconnect.com
Matrix metalloproteinases (MMPs) are the most important proteolytic system for the …
Low-intensity pulsed ultrasound (LIPUS) is a newly approved physical therapy of bone nonunion10 …

[HTML][HTML] Chondro-protective effects of low intensity pulsed ultrasound

SMZ Uddin, B Richbourgh, Y Ding… - Osteoarthritis and …, 2016 - Elsevier
… such as matrix metalloproteinase 13 (MMP13) and A disintegrin and metalloproteinase
with thrombospondin motifs 5 (ADAMTS5) while inhibiting anabolic matrix proteins such as …

Low-intensity pulsed ultrasound promotes aggrecan expression via ZNT-9 in temporomandibular joint chondrocytes

D He, J Wang, Y Li, G Wu, G Zhu, L Chen - Gene, 2021 - Elsevier
… One key feature of TMJ-OA is degeneration of the chondrocyte extracellular matrix (ECM).
Low-intensity pulsed ultrasound (LIPUS) can promote the synthesis of ECM in cartilage. …

Low-intensity pulsed ultrasound induces cartilage matrix synthesis and reduced MMP13 expression in chondrocytes

J Sekino, M Nagao, S Kato, M Sakai, K Abe… - Biochemical and …, 2018 - Elsevier
… MMP13 is a member of the matrix metalloproteinase family of neutral endopeptidases and
is expressed in the skeletal tissue during embryonic development. Chondrocytes and synovial …

The role of low-intensity pulsed ultrasound on cartilage healing in knee osteoarthritis: a review

JB Rothenberg, P Jayaram, U Naqvi, J Gober… - Pm&r, 2017 - Elsevier
Ultrasound (US) is a therapeutic modality that has been used in the treatment of … In recent
years, there have been technological advancements using low-intensity pulsed ultrasound (…