Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells

M Polette, C Gilles, V Marchand, M Seiki… - Clinical & experimental …, 1997 - Springer
… that certain tumor cells might induce the expression of MT1MMP in human fibroblasts, we
treated normal human fibroblasts with the conditioned media of two breast cancer cell lines, …

Significance of membrane type 1 matrix metalloproteinase expression in breast cancer

S Ishigaki, M Toi, T Ueno, H Matsumoto… - … journal of cancer …, 1999 - Wiley Online Library
MMP, is responsible for the activation of MMP2. In this study the significance of MT1-MMP
expression in human breast tumorsMT1MMP expression was detected in tumor cells and/or …

… tethered matrix metalloproteinase MT1-MMP triggers an outside-in DNA damage response that impacts chemo-and radiotherapy responses of breast cancer

V Thakur, K Zhang, A Savadelis, P Zmina, B Aguila… - Cancer letters, 2019 - Elsevier
… by which triple negative breast cancer cells may better withstand genotoxic … matrix
metalloproteinase MT1-MMP. We show that inhibition of MT1-MMP is sufficient to sensitize cells to IR …

Expression of MMP2 and MMP9, their inhibitors, and the activator MT1MMP in primary breast carcinomas

JL Jones, P Glynn, RA Walker - The Journal of pathology, 1999 - Wiley Online Library
… The aim of the present study was to investigate whether MT1-MMP plays a role in breast
carcinoma and whether the immunohistochemical localization of the gelatinases …

Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model

G Bouchard, H Therriault, S Geha, R Bujold… - … Journal of Cancer, 2017 - nature.com
… triple-negative breast cancer (… treatment. In this study, an animal model of TNBC was used
to determine whether the expression of the cell membrane protease MT1-MMP in cancer cells

MT1-MMP and MMP-7 in invasion and metastasis of human cancers

T Shiomi, Y Okada - Cancer and metastasis reviews, 2003 - Springer
… Brown PD, Bloxidge RE, Anderson E, Howell A: Expression of activated gelatinase in human
invasive breast carcinoma. Clin Exp Metastasis 11: 183–189, 1993 17. Brown PD, Bloxidge …

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

C Lodillinsky, E Infante, A Guichard, R Chaligne… - Oncogene, 2016 - nature.com
MT1-MMP levels in foci of invasive carcinoma cells we found in clinical samples of microinvasive
breast cancer… in response to cell adhesion signaling in DCIS.com tumor cells contacting …

TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion

C Chevalier, G Collin, S Descamps… - Nature …, 2016 - nature.com
… in breast tumour cells by overexpressing TOM1L1 in the ERBB2- and TOM1L1-negative breast
cancer cell … (d) Western blot showing MT1-MMP expression in 12 breast cancer cell lines. …

A membrane-type-1 matrix metalloproteinase (MT1-MMP)–discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells

D Assent, I Bourgot, B Hennuy, P Geurts, A Noël… - PLoS …, 2015 - journals.plos.org
… that poorly invasive breast adenocarcinoma cells that do not express MT1-MMP undergo …
invading carcinoma cells [38]. The expression of MT1-MMP was sufficient to confer cancer cells

The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by αVβ3 integrin in human breast cancer cells

K Borrirukwanit, MA Lafleur, FA Mercuri, T Blick… - Matrix biology, 2007 - Elsevier
MMP-2 activation in response to Col I in breast cancer cells, we transduced three different
breast cancer cell … : MCF-7 cells transfected with MT1-MMP (MCF-7–MT1) but expressing low …