… in the metastatic breast cancer cell line MDA-MB-231, retromer regulates the matrix
invasion activity by recycling matrix metalloprotease, MT1-MMP. We further found that MT2-MMP, …

… the MT1-MMP effects. Codistribution of MT1-MMP with Ln-5 in colon and breast cancer tissue
… Thus, Ln-5 cleavage by MMPs may be a widespread mechanism that triggers migration in …

… We have recently demonstrated that in breast carcinoma MCF7 cells MT1-MMP processes …
resistant to MT1-MMP proteolysis. The processing of the α v subunit by MT1-MMP facilitated α …

… We herein report that breast cancer cell invasion and … blocks the lung metastasis of breast
tumors in MMTV-Neu … the plasma membrane localization of MT1-MMP, invadopodia formation, …

… that activation in the cellular model system was due to MT1-MMP/gelatinase A and … A and
MT1-MMP. This new activation cascade may be significant in human breast cancer pathology, …

… Our study was undertaken to localize and identify the MT1-MMP expressing cells in human
breast adenocarcinomas. A textural analysis of images obtained by immunohistochemistry …

… breast carcinoma cells is mediated by membrane type 1-matrix metalloproteinase (MT1-MMP…
Here, we identify MT1-MMP as a novel interacting partner of dual-specificity LIM Kinase-1 …

… may suggest that an invasive potential of breast carcinoma is already obtained before
morphologically overt invasive growth is observed. We believe that further study is war …

… The role of RAB2A in the control of matrix degradation and mammary carcinoma cell invasion
and the alteration in CNV detected in human cancer suggest that elevated levels of this …

… breast cancer in clinical practice [23]. In the present study, to develop an SPECT probe for
breast cancer … preparing a 99m Tc-labeled MT1-MMP targeted imaging agent. The preparation…