… 10) and to further analyze possible effects of PG on the MDA-MB-435 breast cancer cell
line we studied cell transmigration and Matrigel-invasion. PG had no effect on their migration …

… MMP-13 and human MT1-MMP by the MDA-MB-231 tumour … role of the different MMPs in
breast cancer is not fully understood… placed on the MMPs produced by cancer cell lines in vitro, …

… of MT1MMP plays an important role in MT1-MMP-mediated endothelial cell migration on a
… 1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells. J. …

… MT1MMP in the media was Mr 56,000, which was 4,000-Mr smaller than that in the cell
lysates. Northern blot analysis demonstrated that the mRNA expression level of MT1-MMP is …

… in a number of cell lines. Overexpression of MT1-MMP in the normally poorly tumorigenic
breast cancer cell line MCF-7 leads to increased tumour growth, angiogenesis and metastasis, …

… MT1MMP on tumor cell membrane. Thus the Au clusters can specifically target MT1-MMP
on … Moreover, we also chose human breast cancer (MCF-7) cells with low expression of MT1-…

… MT1-MMP, gelatinase A, and EMMPRIN in breast tumors. Formalin-fixed paraffin-embedded
breast … Note the co-expression and co-localization of MT1MMP and EMMPRIN in tumor cells…

… As observed by TIRF microscopy, MT1-MMP-mCherry and … of breast cancer cells to degrade
and invade in a MT1-MMP-… in VAMP7- and MT1-MMP-depleted cells, indicative of a positive-…

… lines, we used the invasive MDA-MB-231 (breast cancer) and Rh41 (ARMS) cell lines that
exhibit high flotillin expression levels (Fig. S1C-E) (Lin et al., 2011; Wang et al., 2013). We …

… To determine the mechanistic aspects of how mDia1 controls MT1-MMP to induce breast
cancer invasion, we first examined whether knockdown or overexpression of mDia1 regulates …