[HTML][HTML] ELK3 expression correlates with cell migration, invasion, and membrane type 1-matrix metalloproteinase expression in MDA-MB-231 breast cancer cells

SH Heo, JY Lee, KM Yang, KS Park - Gene expression, 2015 - ncbi.nlm.nih.gov
… the regulation of MT1-MMP transcription. This study assessed the function of ELK3 in breast
cancer (BC) cells by comparing its expression between basal and luminal cells in silico and …

Interference-free SERS nanoprobes for labeling and imaging of MT1-MMP in breast cancer cells

D Zhu, A Li, Y Di, Z Wang, J Shi, X Ni, Y Wang - Nanotechnology, 2021 - iopscience.iop.org
matrix metalloproteinase (MT1-MMP) in cancer cells is critical for understanding the development,
invasion and metastasis of cancers… expression of MT1-MMP in breast cancer cells has …

CD44 regulates pancreatic cancer invasion through MT1-MMP

W Jiang, Y Zhang, KT Kane, MA Collins… - Molecular Cancer …, 2015 - AACR
… human pancreatic cancer and … MT1-MMP expression in human pancreatic cancer cell
lines. F, Matrigel invasion assay (left) of human pancreatic cancer cell lines treated with MT1-MMP

MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal …

AM Tester, N Ruangpanit, RL Anderson… - Clinical & experimental …, 2000 - Springer
… vimentin expression, MT1MMP expression and stellate … cells, the 67NR cells still express
MT1-MMP at a level that would be sufficient for human breast cancer cells to activate pro-MMP-2…

Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer

DV Rozanov, AY Savinov, R Williams, K Liu… - Cancer research, 2008 - AACR
… of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in
oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells. …

MT1-MMP activation of TGF-β signaling enables intercellular activation of an epithelial-mesenchymal transition program in cancer

HL Nguyen, P Kadam, A Helkin, K Cao… - Current cancer drug …, 2016 - ingentaconnect.com
… of MT1-MMP or Wnt5a can reverse EMT in cancer cells expressing high endogenous MT1-MMP.
… Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines. …

[HTML][HTML] Targeting MT1-MMP as an immunoPET-based strategy for imaging gliomas

AG De Lucas, AJ Schuhmacher, M Oteo, E Romero… - PLoS …, 2016 - journals.plos.org
… Eleven mice bearing breast cancer cells (non-expressing MT1-MMP) in one flank and GBM
cells (expressing MT1-MMP) in the contralateral side were injected iv (tail vein) with 1.5 MBq …

Down-regulation of MT1-MMP expression suppresses tumor cell invasion in metastatic human SW626 ovarian cancer cells

M Wu, G Xu, L Xi, J Wei, A Song, Z Han… - Oncology …, 2006 - spandidos-publications.com
MMP-2 is always activated (4,7,8). We found increased expression of MT1MMP in human
ovarian cancer cellsMMP-2 in cell conditioned medium. To confirm that the activation ratio of …

Calcium influx inhibits MT1MMP processing and blocks MMP2 activation

M Yu, H Sato, M Seiki, S Spiegel, EW Thompson - FEBS letters, 1997 - Wiley Online Library
… Because we have found that MT1-MMP expression correlates best with both … ]MMP-2
activation in human breast cancer cells, we further examined the effect of ionomycin on MT1-MMP

[HTML][HTML] Non-destructive and selective imaging of the functionally active, pro-invasive membrane type-1 matrix metalloproteinase (MT1-MMP) enzyme in cancer cells

AG Remacle, SA Shiryaev, VS Golubkov… - Journal of Biological …, 2013 - ASBMB
… the cell surface-associated active MT1-MMP enzyme in multiple cancer cell types, including
breast carcinoma… , active cellular MT1-MMP enzyme are roughly equal to 1 × 10 5 molecules/…