Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells

WG Jiang, G Davies, TA Martin… - International …, 2006 - spandidos-publications.com
… aberrant staining pattern of MT1-MMP in breast cancer, the current study is … MT1MMP mRNA
in breast cancer. The present study is also the first to show a correlation between MT1-MMP

… and prognostic significance of membrane type 1 matrix metalloproteinase (MT1MMP) and MMP9 according to their localization in invasive breast carcinoma

E Mylona, A Nomikos, C Magkou, M Kamberou… - …, 2007 - Wiley Online Library
… The present study was undertaken to gain further insight into the expression pattern of
MT1-MMP and MMP-9 in invasive breast carcinoma. This was assessed in relation to the classical …

MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells

H Pulyaeva, J Bueno, M Polette, P Birembaut… - Clinical & experimental …, 1997 - Springer
… In the current study, we found MT1-MMP mRNA was only present in invasive HBC cell
lines, and further was induced by treatment with Con A, concomitant with the induced …

MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis

G Yao, P He, L Chen, X Hu, F Gu, C Ye - Cancer Cell International, 2013 - Springer
… -MMP levels in five breast carcinoma cell lines and correlated these levels with the invasive
activity of breast cancer cells. … that MT1-MMP and VEGF-C enhance the invasive potential of …

Cancer cell–associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors

JY Perentes, ND Kirkpatrick, S Nagano, EY Smith… - Cancer research, 2011 - AACR
… activity, we determined the collagen I degradation and invasive potential of mock and … Here,
we show in an orthotopic model of breast cancer that cancer cell MTI-MMP downregulation …

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

C Lodillinsky, E Infante, A Guichard, R Chaligne… - Oncogene, 2016 - nature.com
… 1 (MT1)-matrix metalloproteinase (MMP), a key component of the BM invasion program,
increases during breast cancer progression at the in situ to invasive breast carcinoma transition. …

Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells

MA Cepeda, JJH Pelling, CL Evered, KC Williams… - Molecular cancer, 2016 - Springer
invasive mammary carcinoma (IMC), to show that the metastatic cell line produces little
MT1-MMP protein, consistent with our conclusions using MCF-7 and MDA-MB 231 breast cancer

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

C Rossé, C Lodillinsky, L Fuhrmann… - Proceedings of the …, 2014 - National Acad Sciences
… F-actin–rich puncta on MT1-MMP–positive endosomes and … MT1-MMP from late endosome
to the plasma membrane and play an important role in the invasive potential of breast-cancer

[PDF][PDF] Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in Ductal Carcinoma in Situ and Invasive Ductal Carcinoma of the Breast

HJ Kim, C Park, BW Park, H Lee… - Yonsei medical …, 2006 - synapse.koreamed.org
… Brummer's15 and our results of MMP mRNA expression in noninvasive ductal carcinoma
may suggest that an invasive potential of breast carcinoma is already obtained before …

Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function

A Castagnino, A Castro-Castro, M Irondelle… - Oncogene, 2018 - nature.com
… up-regulated in invasive breast cancers and correlates positively with MT1-MMP expression
in TNBCs … Additionally, our results indicate that CORO1C plays a dual function in MT1-MMP-…