MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells

H Pulyaeva, J Bueno, M Polette, P Birembaut… - Clinical & experimental …, 1997 - Springer
… and their tissue inhibitor in human breast pathology. Invasion Metastasis, 13, 31–7. 31. …
collagenase in normal, benign and malignant breast tissue. Am J Pathol, 136, 585–92. 32. …

Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells

WG Jiang, G Davies, TA Martin… - International …, 2006 - spandidos-publications.com
… It has been shown that myofibroblasts from normal mammary tissue can reduce the invasion
of breast cancer cells including MDAMB-231 and MCF-7. This was partly associated with a …

Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation

UM Munoz-Najar, KM Neurath, F Vumbaca, KP Claffey - Oncogene, 2006 - nature.com
… the involvement of the MT1-MMP/MMP-2/tissue inhibitor of metalloproteinase… MT1-MMP in
a poorly invasive breast cancer cell line, T47-D, promoted hypoxia-induced invasion and MMP

Cancer cell–associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors

JY Perentes, ND Kirkpatrick, S Nagano, EY Smith… - Cancer research, 2011 - AACR
… For the detection of MT1-MMP in mice tissues, we used the LEM-2/15.8 clone, a mouse …
Here, we show in an orthotopic model of breast cancer that cancer cell MTI-MMP downregulation …

[HTML][HTML] MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis

G Yao, P He, L Chen, X Hu, F Gu, C Ye - Cancer Cell International, 2013 - Springer
… To identify the expression of MT1-MMP and VEGF-C in the breast cancer tissue
specimens, immunohistochemical analysis was performed. Briefly, paraffin-embedded …

[HTML][HTML] Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer

M Zhang, X Teng, X Guo, Z Li, J Han, L Yao - The Breast, 2013 - Elsevier
MT1-MMP mRNA expression in the breast cancer was significantly higher than in the normal
breast tissue (p < 0.05), the levels of MT1-MMP … increasing size of the tumor, lymph node …

Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue

MA Mohammad, AA Zeeneldin… - Molecular and cellular …, 2012 - Springer
… , MT1-MMP and MMP-2 in BC tissues and confirmed the preclinical evidence that COX-2
increases the expression of MT1-MMP followed by activation of MMP-… of tumor progression and …

[HTML][HTML] … -1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancer

D Al-Raawi, H Abu-El-Zahab, M El-Shinawi… - … journal of clinical and …, 2011 - ncbi.nlm.nih.gov
… In conclusion, overexpression of MT1-MMP by IBC carcinoma tissues may be associated
with disease aggressiveness either directly through inducing cell motility, or indirectly by …

Clinical significance of MT1-MMP mRNA expression in breast cancer

K Mimori, H Ueo, C Shirasaka… - Oncology …, 2001 - spandidos-publications.com
… in breast cancer patients by RT-PCR assay in minute amounts of tissue. We believe this is
an … assay for determining the role of MTl-MMP for metastasis in patients with breast cancer. …

[HTML][HTML] Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells

MA Cepeda, JJH Pelling, CL Evered, KC Williams… - Molecular cancer, 2016 - Springer
… Additionally, we analyzed the level of MT1-MMP protein in human 21 T breast cancer cell …
mammary carcinoma (IMC), to show that the metastatic cell line produces little MT1-MMP