… and MMP-2 activation without changes in MT1-MMP expression. Our studies suggest that
hypoxic tumor microenvironments promote breast cancer invasion through an MT1-MMP-…

… of the in situ–to–invasive transition of breast cancer (BC), it was recently reported that
silencing of MT1-MMP in MCF10DCIS.com human breast tumor cells impaired the ability of this …

… invasion in mammary tumors. Our findings show that cancer cell MT1-MMP expression
promotes cancer cell … To assess the involvement of MT1-MMP in tumor cell migration in vivo, we …

… breast cancer cell line MDA-MB-231 was used. Expression of MT1-MMP in the breast
cancer cell … The in vitro invasion, growth and cell migration were determined on cell lines …

… the importance of MT1-MMP in promoting cell migration, invasion, experimental metastasis
… by MT1-MMP seems to be essential not only for invasion but also for tumour cell growth, in …

… expression, VIM expression, and invasive/metastatic capacity provides evidence for a
potential role of MT1-MMP in breast cancer invasion and metastasis. It is important to note, …

… In the present study, we showed that higher expression levels of VEGF-C correlated with
increased cell invasion in breast cancer cell lines and that antibody inhibition of VEGF-C …

… -2 and MT1-MMP (the proMMP-2/TIMP-2/ MT1-MMP system) … such as the breast carcinomas,
thyroid papillary carcinomas, … MMP-2 and MT1-MMP contribute to the glioma cell invasion …

… -2 and -9 transcript and protein levels, suggesting that this novel relationship is conserved
amongst MT1-MMP positive breast cancer cells. To further analyze the relationship between …

… degradation mediated by high levels of MT1-MMP is not associated with cell migration and
tumourigenesis, while low levels of MT1-MMP promote invasion and vascularization in vivo. …