… Here we describe the isolation of a mouse cDNA homologue to MT4-MMP (mMT4-MMP)
which includes the complete signal sequence and pro-peptide. This has allowed us to express …

… Our results showed that MT6-MMP as well as MT4-MMP were labeled with [ 3 H]ethanolamine
indicating the presence of a GPI unit with incorporated label. In addition, phosphatidyl …

… A similar sequence in MT4- or MT6-MMP has been characterized as a signal anchoring
to … , MT4- and MT6-MMP are clearly different from the transmembrane-type molecules. MT-…

… MMPs and which has been called MT4-MMP tentatively. We also analyze its expression in
human tissues and show that the gene encoding MT4-MMP (MMP-… evidence that MT4-MMP is …

… the membrane type-MMPs (MT-MMPs) constitute a subfamily of plasma membrane-tethered
MMPs … By contrast GPI-anchored MT4- and MT6-MMP lack transmembrane and intracellular …

… of membrane-type 6 matrix metalloproteinase (MT6-MMP, … of MMPs was studied and
compared with MT1-MMP, MT4-… MMP is closer in function to stromelysin-1 than MT1 and MT4-…

… The nucleotide sequences rat MT3-MMP, rat MT3-MMP-del, and human MT3-MMP reported
in this paper have been deposited in the DDBJ, EMBL, and GenBank™ DNA data bases …

… However, pro-MMP-2 is unique in that it is not activated by serine proteinases, … membrane-type
MMP (MT-MMP). Four different members of MT-MMPs (MT1-, MT2-, MT3-, and MT4-MMPs…

… Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP14) is a zinc-dependent type I
… Elevated expression levels of MT1-MMP have been demonstrated to correlate with a poor …

… Recently, studies in our laboratory showed that membrane-type matrix metalloproteinases
(MT-MMPs) … These characteristics of MT4-MMP and MT6-MMP suggest that they play a role in …