Efficacy and tolerability of antidepressants in people aged 65 years or older with major depressive disorder–a systematic review and a meta-analysis

A Tham, U Jonsson, G Andersson, A Söderlund… - Journal of affective …, 2016 - Elsevier
Background There has been a steady increase in the prescription of antidepressants for the
elderly. This study comprises a systematic review of randomized, placebo-controlled trials of …

[HTML][HTML] Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database

C Coupland, T Hill, R Morriss, M Moore, A Arthur… - BMC medicine, 2018 - Springer
Background Antidepressants are one of the most commonly prescribed medications in
young and middle-aged adults, but there is relatively little information on their safety across …

Treatment indications and potential offlabel use of antidepressants among older adults: A populationbased descriptive study in Denmark

K IshtiakAhmed, X Liu… - … Journal of Geriatric …, 2022 - Wiley Online Library
Objectives Offlabel prescriptions of antidepressants may be of special concern in older
adults. We aimed to study the potential offlabel use of antidepressants among adults≥ 65 …

Antidepressant use in geriatric populations: the burden of side effects and interactions and their impact on adherence and costs

TL Mark, VN Joish, JW Hay, DV Sheehan… - The American journal of …, 2011 - Elsevier
Objectives The study aimed to determine the prevalence of documented side effects and
drug–drug interactions in older adults using antidepressants and their implications for …

Antidepressant treatment patterns in younger and older adults from the general population in a reallife setting

F Etchepare, T Sanglier, M André… - … journal of geriatric …, 2014 - Wiley Online Library
Objective The treatment of depression in reallife settings appears to be influenced by
health care systems. Antidepressant drugs have been found to be underused in the older …

Antidepressants in elderly: metaregression of double-blind, randomized clinical trials

R Calati, MS Signorelli, M Balestri, A Marsano… - Journal of Affective …, 2013 - Elsevier
BACKGROUND: Depression is common in the elderly and in the last few years this led to a
significant increase in antidepressant prescription rates. However, little is known about …

The efficacy, safety and tolerability of antidepressants in late life depression: a meta-analysis

N Mittmann, N Herrmann, TR Einarson… - Journal of affective …, 1997 - Elsevier
Background: To determine the efficacy, safety and tolerability of antidepressants in
depressed elderly patients. Methods: Search for randomized controlled double-blind studies …

[HTML][HTML] Systematic review and meta-analysis of second-generation antidepressants for the treatment of older adults with depression: questionable benefit and …

L Mallery, T MacLeod, M Allen, P McLean-Veysey… - BMC geriatrics, 2019 - Springer
Background Frail older adults are commonly prescribed antidepressants. Yet, there is little
evidence to determine the efficacy and safety of antidepressants to treat depression with …

Antidepressant use and mortality in Finland: a register-linkage study from a nationwide cohort

J Haukka, M Arffman, T Partonen, S Sihvo… - European journal of …, 2009 - Springer
Background It is generally acknowledged that depressed patients need specific attention
during the first weeks after initiation of antidepressant (AD) treatment because of the …

[HTML][HTML] Maintenance use of antidepressants in Dutch general practice: non-guideline concordant

E Piek, BJ Kollen, K van der Meer, BWJH Penninx… - PloS one, 2014 - journals.plos.org
Background There is hardly evidence on maintenance treatment with antidepressants in
primary care. Nevertheless, depression guidelines recommend maintenance treatment ie …