Background: Antidepressant use is highly prevalent. Research has mainly focused on
efficacy during short periods of use for depression and anxiety. There is a relative paucity of …

Approximately 14% of older Americans are now taking an antidepressant. 1–3 However, this
broad use has not been associated with a notable decrease in the burden of geriatric …

A systematic review and random-effects model network meta-analysis were conducted to
compare the efficacy, acceptability, tolerability, and safety of antidepressants to treat adults …

Objectives Depression in older adults is often undertreated due, in part, to medication costs.
We examined the impact of improved prescription drug coverage under Medicare Part D on …

Purpose Clinical guidelines recommend that antidepressant treatment should be continued
for at least 6 months. We examined persistence in patients initiated on an antidepressant …

Objective To quantify the extent and identify predictors of potentially inappropriate
antidepressant use among older adults with dementia and newly diagnosed major …

Purpose The number of antidepressants prescribed in the UK has been increasing over the
last 25 years; however, the reasons for this are not clear. This study examined trends in …

Antidepressant drug trials have been criticised because they study atypical populations of
depressive patients. The present cross-sectional database analysis was designed to define …

To determine the feasibility and effectiveness of treatments for depressed elderly medical
inpatients, MEDLINE was searched for potentially relevant articles published from January …

Background Depression is a relatively common experience in older adults. The syndrome is
associated with considerable distress, morbidity and service commitment. Approximately two …