Ongoing changes in available agents and health care delivery systems have made it
imperative to study the quality of antidepressant use in vulnerable and traditionally …

BackgroundAlthough the efficacy of antidepressants has been demonstrated in randomised,
controlled clinical trials, it is how an antidepressant is used in clinical practice that …

Purpose To investigate the prevalence and incidence of antidepressant (AD) use in the
elderly during an 8-year period and to evaluate AD treatment appropriateness. Methods A …

Objective Metaanalyses of antidepressant drug treatment trials have found that increasing
age is associated with a less favourable outcome. Because the prevalence of geriatric …

Objective Concurrent polypharmacy and potentially-inappropriate-medication (PIMs) use
with antidepressants in older adults is understudied. We investigated the prevalence and …

Background: Generally, the efforts to predict antidepressant use from patient demographic
factors have not been fruitful. Aim: Our objective was to generate hypotheses regarding …

Objectives To establish the comparative efficacy and safety of selective serotonin reuptake
inhibitors and serotoninnorepinephrine reuptake inhibitors in older adults using the …

Method: Electronic records data from 4 large health care systems identified outpatients aged
18 years or older starting a new episode of antidepressant treatment in 2011 with an ICD-9 …

Antidepressant prescribing patterns and factors influencing the choice of antidepressant for
the treatment of depression were examined in the Factors Influencing Depression Endpoints …

Background. There are few epidemiologic studies of the rate of antidepressant use in the
elderly population, especially for community residents. We report findings on antidepressant …