Functional roles for the cancer cell–associated membrane type I matrix metalloproteinase
(MT1-MMP) during early steps of the metastatic cascade in primary tumors remain …

Background Recent evidence suggests that vascular endothelial growth factor-C (VEGF-C)-
dependent tumour production promotes lymphangiogenesis, while membrane-type matrix 1 …

Membrane-type matrix metalloproteinases (MT-MMP) constitute a subfamily of six distinct
membrane-associated MMPs. Although the contribution of MT1-MMP during different steps …

Membrane-type I matrix metalloproteinase (MT1-MMP) is associated with multiple forms of
cancer including mammary cancer. To directly evaluate the significance of MT1-MMP …

Matrix metalloproteinases (MMPs) are a family of important proteolytic enzymes that play an
important role in the remodeling of the tumor microenvironment and associate with …

Abstract Background Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a
multifunctional protease implicated in metastatic progression ostensibly due to its ability to …

The present study aims at investigating the mechanism by which membranetype 4 matrix
metalloproteinase (MT4MMP), a membraneanchored MMP expressed by human breast …

Membrane type 1-matrix metalloproteinase (MT1-MMP) has been identified to play a
significant role in several types of cancers, but little is known about the significance of MT1 …

Membranetype 4 matrix metalloprotease (MT4MMP) expression in breast
adenocarcinoma stimulates tumor growth and metastatic spreading to the lung. However …

In primary human melanoma, the membrane-type matrix metalloproteinase, MT3-MMP, is
overexpressed in the most aggressive nodular-type tumors. Unlike MT1-MMP and MT2 …