[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
Genomewide association studies: history, rationale, and prospects for psychiatric disorders
Psychiatric GWAS Consortium Coordinating … - Focus, 2010 - Am Psychiatric Assoc
Objective: The authors conducted a review of the history and empirical basis of genomewide
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …
Specific and common genes implicated across major mental disorders: a review of meta-analysis studies
Major efforts have been directed at family-based association and case–control studies to
identify the involvement of candidate genes in the major disorders of mental health. What …
identify the involvement of candidate genes in the major disorders of mental health. What …
[PDF][PDF] Common genetic variants shared among five major psychiatric disorders: a large-scale genome-wide combined analysis
L Xia, K Xia, DR Weinberger, F Zhang - Glob Clin Transl Res, 2019 - gcatresearch.com
Background: Genetic correlation and pleiotropic effects among psychiatric disorders have
been reported. This study aimed to identify specific common genetic variants shared …
been reported. This study aimed to identify specific common genetic variants shared …
Genome-wide association studies in psychiatry: what have we learned?
AL Collins, PF Sullivan - The British Journal of Psychiatry, 2013 - cambridge.org
Genome-wide association studies (GWAS) have been the focus of considerable effort in
psychiatry. These efforts have markedly increased knowledge of the genetic basis of …
psychiatry. These efforts have markedly increased knowledge of the genetic basis of …
Examining the shared etiology of psychopathology with genome-wide association studies
TT Mallard, AD Grotzinger… - Physiological …, 2023 - journals.physiology.org
Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …
The psychiatric genomics consortium: history, development, and the future
HJ Watson, Z Yilmaz, PF Sullivan - Personalized psychiatry, 2020 - Elsevier
Psychiatric genetics is in an era of discovery. Genome-wide association analyses and other
genomic analyses are paving the way for rapid progress in understanding the biological …
genomic analyses are paving the way for rapid progress in understanding the biological …
[图书][B] Psychiatric Genomics
Psychiatric Genomics presents and synthesizes available knowledge in the field of
psychiatric genomics, offering methodologies to advance new research and aid clinical …
psychiatric genomics, offering methodologies to advance new research and aid clinical …
[PDF][PDF] A framework for interpreting genome-wide association studies of psychiatric disorders
Genome-wide association studies (GWAS) have yielded a plethora of new findings in the
past 3 years. By early 2009, GWAS on 47 samples of subjects with attention-deficit …
past 3 years. By early 2009, GWAS on 47 samples of subjects with attention-deficit …
Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice
JL Doherty, MJ Owen - Genome medicine, 2014 - Springer
Psychiatric disorders such as schizophrenia, bipolar disorder, major depressive disorder,
attention-deficit/hyperactivity disorder and autism spectrum disorder are common and result …
attention-deficit/hyperactivity disorder and autism spectrum disorder are common and result …