[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal… - Cell, 2019 - cell.com
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …

Genomewide association studies: history, rationale, and prospects for psychiatric disorders

Psychiatric GWAS Consortium Coordinating … - Focus, 2010 - Am Psychiatric Assoc
Objective: The authors conducted a review of the history and empirical basis of genomewide
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …

Specific and common genes implicated across major mental disorders: a review of meta-analysis studies

JM Gatt, KLO Burton, LM Williams… - Journal of psychiatric …, 2015 - Elsevier
Major efforts have been directed at family-based association and case–control studies to
identify the involvement of candidate genes in the major disorders of mental health. What …

[PDF][PDF] Common genetic variants shared among five major psychiatric disorders: a large-scale genome-wide combined analysis

L Xia, K Xia, DR Weinberger, F Zhang - Glob Clin Transl Res, 2019 - gcatresearch.com
Background: Genetic correlation and pleiotropic effects among psychiatric disorders have
been reported. This study aimed to identify specific common genetic variants shared …

Genome-wide association studies in psychiatry: what have we learned?

AL Collins, PF Sullivan - The British Journal of Psychiatry, 2013 - cambridge.org
Genome-wide association studies (GWAS) have been the focus of considerable effort in
psychiatry. These efforts have markedly increased knowledge of the genetic basis of …

Examining the shared etiology of psychopathology with genome-wide association studies

TT Mallard, AD Grotzinger… - Physiological …, 2023 - journals.physiology.org
Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …

The psychiatric genomics consortium: history, development, and the future

HJ Watson, Z Yilmaz, PF Sullivan - Personalized psychiatry, 2020 - Elsevier
Psychiatric genetics is in an era of discovery. Genome-wide association analyses and other
genomic analyses are paving the way for rapid progress in understanding the biological …

[图书][B] Psychiatric Genomics

EE Tsermpini, M Alda, GP Patrinos - 2022 - books.google.com
Psychiatric Genomics presents and synthesizes available knowledge in the field of
psychiatric genomics, offering methodologies to advance new research and aid clinical …

[PDF][PDF] A framework for interpreting genome-wide association studies of psychiatric disorders

S Cichon, N Craddock, MJ Daly, SV Faraone… - Molecular …, 2009 - research.vu.nl
Genome-wide association studies (GWAS) have yielded a plethora of new findings in the
past 3 years. By early 2009, GWAS on 47 samples of subjects with attention-deficit …

Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice

JL Doherty, MJ Owen - Genome medicine, 2014 - Springer
Psychiatric disorders such as schizophrenia, bipolar disorder, major depressive disorder,
attention-deficit/hyperactivity disorder and autism spectrum disorder are common and result …