Membrane type 1 matrix metalloproteinase (MT1-MMP) is a type I transmembrane MMP
shown to play a critical role in normal development and in malignant processes. Emerging …

The matrix metalloproteinase (MMP) family of extracellular proteinases regulates
development and physiologic events. Genetic analyses using transgenic mice that have …

We have recently identified the fifth member of the membranetype matrix metalloproteinase
subfamily, MT5MMP/MMP24, which is expressed in a brain specific manner (Duanqing Pei …

Matrix metalloproteinases (MMPs) have been implicated not only in the regulation of
developmental processes but also in the release of biologically active molecules and in the …

Membrane-type 1 matrix metalloproteinase (MT1-MMP, MMP-14), a transmembrane
proteinase with a short cytoplasmic tail, is a major effector of extracellular matrix remodeling …

Dentin formation in physiological and pathological conditions has been widely studied, but
the events and regulation are still not completely understood. Odontoblasts, terminally …

Abstract MMP-9 and MMP-2 are metalloproteinases which degrade the denatured collagen
fibers. However, there is no report about roles of these MMPs in the odontogenic region of …

The osteoclasts are the cells responsible for bone resorption. Matrix metalloproteinases
(MMPs) appear crucial for this process. To identify possible MMP expression in osteoclasts …

Tooth eruption involves extensive degradation and reorganization of extracellular matrix
(ECM) components. It is not known how ECM-degrading enzymes are coordinated with each …

Membrane-type-1 matrix metalloproteinase (MT1-MMP) has transmembrane and
cytoplasmic domains, which target it to invasive fronts. We analyzed the role of the …